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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG3
All Species:
35.76
Human Site:
S546
Identified Species:
65.56
UniProt:
Q96JB2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96JB2
NP_113619.1
828
94096
S546
P
R
P
Q
T
T
I
S
P
A
D
L
H
G
M
Chimpanzee
Pan troglodytes
XP_001158886
790
89707
H519
E
A
S
F
S
D
V
H
L
E
E
G
E
S
N
Rhesus Macaque
Macaca mulatta
XP_001096875
828
94056
S546
P
R
P
Q
T
T
I
S
P
A
D
L
H
G
M
Dog
Lupus familis
XP_848489
830
94828
S548
P
R
P
Q
T
T
I
S
P
A
D
L
H
G
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8CI04
820
93264
S538
P
R
P
Q
T
T
I
S
P
A
D
L
H
G
M
Rat
Rattus norvegicus
NP_001012157
828
94228
S546
P
R
P
Q
T
T
I
S
P
A
D
L
H
G
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417041
835
94848
S543
P
R
Q
Q
S
T
I
S
P
A
D
L
H
G
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001137512
820
93798
S539
T
R
L
Q
S
S
V
S
P
A
D
L
H
G
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q961G1
905
101221
S534
Y
T
V
K
Q
M
N
S
P
A
D
L
H
G
M
Honey Bee
Apis mellifera
XP_393867
799
92557
S512
Q
K
T
H
I
G
N
S
P
A
D
L
H
G
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196648
781
87158
S518
I
H
V
N
A
S
L
S
P
A
D
L
H
G
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177485
784
88591
Y508
A
D
V
F
K
T
W
Y
P
P
L
E
K
T
L
Baker's Yeast
Sacchar. cerevisiae
P40094
801
92526
D523
I
D
S
E
E
S
T
D
K
I
S
Q
L
Q
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
98.9
95
N.A.
94.9
96.2
N.A.
N.A.
86.4
N.A.
77
N.A.
40.2
41.5
N.A.
47.5
Protein Similarity:
100
95.4
99.7
97.1
N.A.
96.9
98.1
N.A.
N.A.
92.5
N.A.
87
N.A.
56.4
60.5
N.A.
63.1
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
N.A.
86.6
N.A.
66.6
N.A.
53.3
53.3
N.A.
53.3
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
N.A.
93.3
N.A.
86.6
N.A.
60
60
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.7
21.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.8
43
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
0
0
0
0
77
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
0
0
0
8
0
8
0
0
77
0
0
0
0
% D
% Glu:
8
0
0
8
8
0
0
0
0
8
8
8
8
0
0
% E
% Phe:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
8
0
77
0
% G
% His:
0
8
0
8
0
0
0
8
0
0
0
0
77
0
0
% H
% Ile:
16
0
0
0
8
0
47
0
0
8
0
0
0
0
0
% I
% Lys:
0
8
0
8
8
0
0
0
8
0
0
0
8
0
0
% K
% Leu:
0
0
8
0
0
0
8
0
8
0
8
77
8
0
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
77
% M
% Asn:
0
0
0
8
0
0
16
0
0
0
0
0
0
0
8
% N
% Pro:
47
0
39
0
0
0
0
0
85
8
0
0
0
0
0
% P
% Gln:
8
0
8
54
8
0
0
0
0
0
0
8
0
8
0
% Q
% Arg:
0
54
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
16
0
24
24
0
77
0
0
8
0
0
8
0
% S
% Thr:
8
8
8
0
39
54
8
0
0
0
0
0
0
8
8
% T
% Val:
0
0
24
0
0
0
16
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _