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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG3
All Species:
27.27
Human Site:
Y682
Identified Species:
50
UniProt:
Q96JB2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96JB2
NP_113619.1
828
94096
Y682
T
P
E
I
R
E
H
Y
L
D
S
K
K
D
V
Chimpanzee
Pan troglodytes
XP_001158886
790
89707
I649
T
R
D
A
A
F
K
I
L
N
P
M
T
V
P
Rhesus Macaque
Macaca mulatta
XP_001096875
828
94056
Y682
T
P
E
I
R
E
H
Y
L
D
S
K
K
D
V
Dog
Lupus familis
XP_848489
830
94828
Y684
T
P
E
I
R
E
H
Y
L
D
S
K
K
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8CI04
820
93264
Y674
T
P
E
I
R
E
H
Y
L
D
S
K
K
D
V
Rat
Rattus norvegicus
NP_001012157
828
94228
Y682
T
P
E
I
R
E
H
Y
L
D
S
K
K
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417041
835
94848
Y679
T
P
E
I
R
E
H
Y
I
D
S
K
K
D
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001137512
820
93798
Y675
T
P
E
I
K
E
H
Y
I
D
S
K
K
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q961G1
905
101221
L668
T
P
Q
I
K
E
H
L
L
D
S
R
K
E
V
Honey Bee
Apis mellifera
XP_393867
799
92557
L645
A
P
Q
M
K
E
Q
L
I
D
S
R
K
H
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196648
781
87158
G647
F
L
E
F
L
F
E
G
A
P
Q
V
T
E
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177485
784
88591
K635
E
S
Q
I
D
A
K
K
E
L
E
K
C
L
K
Baker's Yeast
Sacchar. cerevisiae
P40094
801
92526
M663
V
P
K
V
V
N
N
M
V
D
A
R
T
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
98.9
95
N.A.
94.9
96.2
N.A.
N.A.
86.4
N.A.
77
N.A.
40.2
41.5
N.A.
47.5
Protein Similarity:
100
95.4
99.7
97.1
N.A.
96.9
98.1
N.A.
N.A.
92.5
N.A.
87
N.A.
56.4
60.5
N.A.
63.1
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
N.A.
93.3
N.A.
86.6
N.A.
66.6
40
N.A.
6.6
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
N.A.
100
N.A.
100
N.A.
93.3
73.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.7
21.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.8
43
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
8
8
0
0
8
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
8
0
8
0
0
0
0
77
0
0
0
54
0
% D
% Glu:
8
0
62
0
0
70
8
0
8
0
8
0
0
24
0
% E
% Phe:
8
0
0
8
0
16
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
62
0
0
0
0
0
0
8
8
% H
% Ile:
0
0
0
70
0
0
0
8
24
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
24
0
16
8
0
0
0
62
70
0
8
% K
% Leu:
0
8
0
0
8
0
0
16
54
8
0
0
0
8
8
% L
% Met:
0
0
0
8
0
0
0
8
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
8
8
0
0
8
0
0
0
0
0
% N
% Pro:
0
77
0
0
0
0
0
0
0
8
8
0
0
0
8
% P
% Gln:
0
0
24
0
0
0
8
0
0
0
8
0
0
0
0
% Q
% Arg:
0
8
0
0
47
0
0
0
0
0
0
24
0
0
0
% R
% Ser:
0
8
0
0
0
0
0
0
0
0
70
0
0
0
0
% S
% Thr:
70
0
0
0
0
0
0
0
0
0
0
0
24
0
0
% T
% Val:
8
0
0
8
8
0
0
0
8
0
0
8
0
8
70
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _