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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIC2
All Species:
18.18
Human Site:
Y425
Identified Species:
50
UniProt:
Q96JB3
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96JB3
NP_055909.2
615
66156
Y425
S
G
H
A
S
A
H
Y
M
Y
R
Q
E
G
Y
Chimpanzee
Pan troglodytes
XP_515003
615
66212
Y425
S
G
H
A
S
A
H
Y
M
Y
R
Q
E
G
Y
Rhesus Macaque
Macaca mulatta
XP_001086914
681
71752
Y425
S
G
H
A
S
A
H
Y
M
Y
R
Q
E
G
Y
Dog
Lupus familis
XP_543570
635
68437
Y445
S
G
H
A
G
T
H
Y
V
Y
R
Q
E
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLZ6
672
72654
Y482
S
G
H
T
G
A
H
Y
V
Y
R
Q
E
G
Y
Rat
Rattus norvegicus
O88553
601
68080
E403
E
I
P
Y
E
C
N
E
C
G
K
A
F
K
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90850
676
73740
C422
L
G
D
N
L
Y
V
C
I
P
C
G
K
G
F
Frog
Xenopus laevis
P18729
336
37535
T65
G
E
K
P
F
T
C
T
E
C
G
K
N
F
A
Zebra Danio
Brachydanio rerio
Q90W33
560
62581
Y373
R
N
S
A
N
Y
V
Y
R
Q
E
G
F
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
79.3
90.8
N.A.
80.9
22.1
N.A.
N.A.
44.6
20.4
55.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
81.7
92.7
N.A.
84.2
38.2
N.A.
N.A.
53.2
30.4
66.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
80
6.6
N.A.
N.A.
13.3
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
20
N.A.
N.A.
33.3
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
56
0
45
0
0
0
0
0
12
0
0
12
% A
% Cys:
0
0
0
0
0
12
12
12
12
12
12
0
0
0
0
% C
% Asp:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
12
12
0
0
12
0
0
12
12
0
12
0
56
12
0
% E
% Phe:
0
0
0
0
12
0
0
0
0
0
0
0
23
12
12
% F
% Gly:
12
67
0
0
23
0
0
0
0
12
12
23
0
67
0
% G
% His:
0
0
56
0
0
0
56
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
0
0
12
0
0
0
0
0
0
% I
% Lys:
0
0
12
0
0
0
0
0
0
0
12
12
12
12
0
% K
% Leu:
12
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
34
0
0
0
0
0
0
% M
% Asn:
0
12
0
12
12
0
12
0
0
0
0
0
12
0
0
% N
% Pro:
0
0
12
12
0
0
0
0
0
12
0
0
0
0
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
12
0
56
0
0
0
% Q
% Arg:
12
0
0
0
0
0
0
0
12
0
56
0
0
0
0
% R
% Ser:
56
0
12
0
34
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
12
0
23
0
12
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
23
0
23
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
23
0
67
0
56
0
0
0
0
67
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _