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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK5RAP3
All Species:
42.12
Human Site:
Y239
Identified Species:
66.19
UniProt:
Q96JB5
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96JB5
NP_788276.1
506
56921
Y239
K
R
G
N
S
T
V
Y
E
W
R
T
G
T
E
Chimpanzee
Pan troglodytes
XP_511931
506
56960
Y239
K
R
G
N
S
T
V
Y
E
W
R
T
G
T
E
Rhesus Macaque
Macaca mulatta
XP_001085224
506
56817
Y239
K
R
G
N
S
T
V
Y
E
W
R
T
G
T
E
Dog
Lupus familis
XP_537662
649
72618
Y383
R
R
G
N
S
T
V
Y
E
W
R
M
G
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99LM2
503
56972
Y238
K
K
G
N
S
T
V
Y
E
W
R
T
G
T
E
Rat
Rattus norvegicus
Q9JLH7
504
57026
Y238
P
K
G
N
S
T
V
Y
E
W
R
T
G
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505442
312
34815
Y94
L
Y
E
K
D
N
T
Y
L
A
E
L
A
S
L
Chicken
Gallus gallus
NP_001026757
511
57121
Y242
S
K
G
N
T
T
V
Y
E
W
R
T
G
F
E
Frog
Xenopus laevis
NP_001089976
508
57551
Y238
K
C
G
D
T
T
I
Y
E
W
R
V
G
E
A
Zebra Danio
Brachydanio rerio
NP_001002105
507
57328
Y237
K
K
G
N
T
T
V
Y
E
R
K
T
G
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95SK3
509
57724
A241
I
H
K
E
A
P
L
A
V
E
E
P
P
I
R
Honey Bee
Apis mellifera
XP_001123188
487
56241
Y244
D
K
G
N
T
T
T
Y
E
W
I
Y
G
E
A
Nematode Worm
Caenorhab. elegans
Q9U2Y2
489
55713
Y241
R
G
L
D
V
T
T
Y
E
W
K
Y
N
Q
K
Sea Urchin
Strong. purpuratus
XP_785908
502
57494
Y251
Q
H
G
N
T
R
V
Y
Q
W
R
T
G
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FG23
549
62111
F247
N
P
P
S
L
S
V
F
G
D
S
E
G
L
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.8
72.4
N.A.
88.1
87.1
N.A.
48.4
64.7
57.6
62.9
N.A.
37.1
40.3
40.3
48.4
Protein Similarity:
100
99.8
99.5
75.1
N.A.
94
93.8
N.A.
54.3
79.8
77.3
81.4
N.A.
55.7
58.8
58.2
69.5
P-Site Identity:
100
100
100
86.6
N.A.
93.3
86.6
N.A.
6.6
73.3
53.3
60
N.A.
0
46.6
26.6
53.3
P-Site Similarity:
100
100
100
93.3
N.A.
100
93.3
N.A.
13.3
86.6
73.3
80
N.A.
13.3
60
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
7
0
7
0
0
7
0
14
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
14
7
0
0
0
0
7
0
0
0
0
7
% D
% Glu:
0
0
7
7
0
0
0
0
74
7
14
7
0
14
47
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% F
% Gly:
0
7
74
0
0
0
0
0
7
0
0
0
80
0
0
% G
% His:
0
14
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
7
0
0
0
7
0
0
7
0
% I
% Lys:
40
34
7
7
0
0
0
0
0
0
14
0
0
7
7
% K
% Leu:
7
0
7
0
7
0
7
0
7
0
0
7
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
7
0
0
67
0
7
0
0
0
0
0
0
7
7
0
% N
% Pro:
7
7
7
0
0
7
0
0
0
0
0
7
7
0
0
% P
% Gln:
7
0
0
0
0
0
0
0
7
0
0
0
0
7
0
% Q
% Arg:
14
27
0
0
0
7
0
0
0
7
60
0
0
0
7
% R
% Ser:
7
0
0
7
40
7
0
0
0
0
7
0
0
7
0
% S
% Thr:
0
0
0
0
34
74
20
0
0
0
0
54
0
40
0
% T
% Val:
0
0
0
0
7
0
67
0
7
0
0
7
0
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
74
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
87
0
0
0
14
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _