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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EAF1
All Species:
33.03
Human Site:
S260
Identified Species:
60.56
UniProt:
Q96JC9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96JC9
NP_149074.3
268
29042
S260
L
R
N
D
L
Q
L
S
E
S
G
S
D
S
D
Chimpanzee
Pan troglodytes
XP_001159232
357
38294
S349
L
R
N
D
L
Q
L
S
E
S
G
S
D
S
D
Rhesus Macaque
Macaca mulatta
XP_001082128
344
36861
S336
L
R
N
D
L
Q
L
S
E
S
G
S
D
S
D
Dog
Lupus familis
XP_542776
299
32439
M260
L
S
K
I
S
Y
G
M
A
T
Y
P
L
G
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9D4C5
268
28948
S260
L
R
N
D
L
Q
L
S
E
S
G
S
D
S
D
Rat
Rattus norvegicus
Q811X5
262
28914
S254
L
R
S
D
L
Q
L
S
E
S
D
S
D
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514534
254
27236
E247
R
N
D
L
Q
L
S
E
S
G
S
D
S
D
D
Chicken
Gallus gallus
Q5ZHP7
264
28989
S256
L
R
S
D
L
Q
L
S
E
S
G
S
D
S
D
Frog
Xenopus laevis
NP_001085950
293
32028
Y253
L
M
N
T
L
S
K
Y
C
L
L
G
S
V
H
Zebra Danio
Brachydanio rerio
NP_001002115
253
27530
S246
N
D
L
Q
L
S
E
S
G
S
D
S
D
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7JRJ1
504
54910
S446
L
P
N
L
G
L
G
S
I
S
P
A
Y
G
S
Honey Bee
Apis mellifera
XP_394906
317
33904
S257
D
S
D
E
G
A
L
S
D
S
T
S
S
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787179
315
33670
S306
L
S
E
D
L
Q
L
S
E
S
G
S
D
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75
74.1
88.2
N.A.
98.1
52.6
N.A.
76.8
52.6
71.3
75
N.A.
27.5
33.4
N.A.
36.5
Protein Similarity:
100
75
74.1
88.9
N.A.
98.5
64.5
N.A.
82.8
68.2
77.8
82.8
N.A.
38
47.6
N.A.
53.3
P-Site Identity:
100
100
100
6.6
N.A.
100
80
N.A.
6.6
93.3
20
40
N.A.
26.6
33.3
N.A.
86.6
P-Site Similarity:
100
100
100
13.3
N.A.
100
93.3
N.A.
13.3
100
20
40
N.A.
33.3
53.3
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
8
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
8
16
54
0
0
0
0
8
0
16
8
62
8
62
% D
% Glu:
0
0
8
8
0
0
8
8
54
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
16
0
16
0
8
8
47
8
0
16
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% H
% Ile:
0
0
0
8
0
0
0
0
8
0
0
0
0
8
0
% I
% Lys:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
77
0
8
16
70
16
62
0
0
8
8
0
8
0
0
% L
% Met:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
8
8
47
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
8
8
0
0
0
% P
% Gln:
0
0
0
8
8
54
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
47
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
24
16
0
8
16
8
77
8
77
8
70
24
62
16
% S
% Thr:
0
0
0
8
0
0
0
0
0
8
8
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
8
0
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _