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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AKR1E2
All Species:
8.48
Human Site:
S138
Identified Species:
20.74
UniProt:
Q96JD6
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96JD6
NP_001035267.1
320
36589
S138
Q
D
L
P
L
D
E
S
N
M
V
I
P
S
D
Chimpanzee
Pan troglodytes
XP_001153988
427
47519
S245
Q
D
L
P
L
D
E
S
N
M
V
I
P
S
D
Rhesus Macaque
Macaca mulatta
XP_001103302
320
36412
S138
H
D
L
P
L
D
E
S
D
M
V
I
P
G
D
Dog
Lupus familis
XP_851036
436
48778
P165
L
D
R
L
L
N
K
P
N
L
R
F
K
P
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCT1
301
34442
V122
P
L
D
R
N
G
K
V
I
P
S
H
T
S
F
Rat
Rattus norvegicus
Q5U1Y4
301
34481
V122
P
L
D
R
S
G
K
V
I
P
S
H
T
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512123
306
34973
E136
L
D
T
W
E
A
M
E
E
L
V
D
V
G
L
Chicken
Gallus gallus
NP_989960
317
36454
E147
L
D
T
W
E
A
M
E
E
L
V
D
C
G
K
Frog
Xenopus laevis
NP_001083398
318
36045
G146
R
F
L
D
T
W
E
G
M
E
E
L
V
D
A
Zebra Danio
Brachydanio rerio
Q6AZW2
324
36744
L149
T
W
A
A
M
E
K
L
V
D
Q
G
L
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74
94
51.8
N.A.
70.6
70.9
N.A.
60
60.6
57.1
48.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
74.4
97.1
60
N.A.
81.5
82.1
N.A.
74
75
70.3
65.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
80
20
N.A.
6.6
6.6
N.A.
13.3
13.3
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
40
N.A.
13.3
13.3
N.A.
20
20
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
20
0
0
0
0
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
60
20
10
0
30
0
0
10
10
0
20
0
10
30
% D
% Glu:
0
0
0
0
20
10
40
20
20
10
10
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
20
% F
% Gly:
0
0
0
0
0
20
0
10
0
0
0
10
0
30
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
20
0
0
30
0
0
10
% I
% Lys:
0
0
0
0
0
0
40
0
0
0
0
0
10
0
20
% K
% Leu:
30
20
40
10
40
0
0
10
0
30
0
10
10
0
10
% L
% Met:
0
0
0
0
10
0
20
0
10
30
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
10
0
0
30
0
0
0
0
0
0
% N
% Pro:
20
0
0
30
0
0
0
10
0
20
0
0
30
10
0
% P
% Gln:
20
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
10
0
10
20
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
0
0
0
10
0
0
30
0
0
20
0
0
40
0
% S
% Thr:
10
0
20
0
10
0
0
0
0
0
0
0
20
0
0
% T
% Val:
0
0
0
0
0
0
0
20
10
0
50
0
20
0
0
% V
% Trp:
0
10
0
20
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _