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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC16B All Species: 22.73
Human Site: T423 Identified Species: 55.56
UniProt: Q96JE7 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96JE7 NP_149118.2 1060 116604 T423 W P V L S S G T P N L L T G E
Chimpanzee Pan troglodytes XP_514022 1060 116651 T423 W P V L S S G T P N L L T G E
Rhesus Macaque Macaca mulatta XP_001105806 1061 116833 T423 W P V L S S G T P N L L T G E
Dog Lupus familis XP_547449 1046 115517 T413 W P V L S S G T P N L L T G E
Cat Felis silvestris
Mouse Mus musculus Q91XT4 1051 115505 T415 W P V L S S G T R D L L T G E
Rat Rattus norvegicus Q75N33 1057 116878 T415 W P V L S S G T R N L L T G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515582 977 108903 V375 C R Q N G S M V G S D T A E L
Chicken Gallus gallus Q6AW68 929 102937 L326 D S A L L W K L L V L L C R Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_695457 2216 240508 Q1441 H A E E D M G Q M S L L S D T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393378 2058 236305 S1037 S I Q G N Q D S V I G S E K I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 93.5 76.6 N.A. 73.2 73.1 N.A. 49.3 46.5 N.A. 22.2 N.A. N.A. 20.2 N.A. N.A.
Protein Similarity: 100 98.4 95.5 82.9 N.A. 80.9 80.8 N.A. 62.2 57.7 N.A. 30.4 N.A. N.A. 31.1 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 86.6 93.3 N.A. 6.6 20 N.A. 20 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 13.3 26.6 N.A. 33.3 N.A. N.A. 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 0 0 0 0 0 0 0 0 10 0 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 10 0 0 0 10 0 10 0 0 10 10 0 0 10 0 % D
% Glu: 0 0 10 10 0 0 0 0 0 0 0 0 10 10 60 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 10 0 70 0 10 0 10 0 0 60 0 % G
% His: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 10 % I
% Lys: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 0 % K
% Leu: 0 0 0 70 10 0 0 10 10 0 80 80 0 0 10 % L
% Met: 0 0 0 0 0 10 10 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 10 0 0 0 0 50 0 0 0 0 0 % N
% Pro: 0 60 0 0 0 0 0 0 40 0 0 0 0 0 0 % P
% Gln: 0 0 20 0 0 10 0 10 0 0 0 0 0 0 10 % Q
% Arg: 0 10 0 0 0 0 0 0 20 0 0 0 0 10 0 % R
% Ser: 10 10 0 0 60 70 0 10 0 20 0 10 10 0 0 % S
% Thr: 0 0 0 0 0 0 0 60 0 0 0 10 60 0 10 % T
% Val: 0 0 60 0 0 0 0 10 10 10 0 0 0 0 0 % V
% Trp: 60 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _