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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNF594
All Species:
7.58
Human Site:
S249
Identified Species:
27.78
UniProt:
Q96JF6
Number Species:
6
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96JF6
NP_115919.1
807
93907
S249
N
K
C
G
K
A
F
S
Q
S
T
D
L
I
I
Chimpanzee
Pan troglodytes
XP_523843
1120
130265
S249
N
K
C
G
K
A
F
S
Q
S
T
D
L
I
I
Rhesus Macaque
Macaca mulatta
XP_001099720
674
78723
D152
R
N
F
Q
G
S
S
D
L
I
T
H
Q
V
T
Dog
Lupus familis
XP_541659
1259
145674
I349
K
E
C
G
K
A
F
I
R
G
S
H
L
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8C827
914
104793
S281
D
T
C
G
K
T
F
S
N
S
S
G
L
R
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520702
737
83549
E215
I
Q
P
S
N
L
I
E
H
Q
I
I
H
S
G
Chicken
Gallus gallus
Frog
Xenopus laevis
P08045
1350
155787
A258
P
L
C
V
K
R
F
A
E
S
S
A
L
M
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.8
58.3
38.8
N.A.
40.4
N.A.
N.A.
46.7
N.A.
30.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
71.5
67.7
47.9
N.A.
56.7
N.A.
N.A.
59.9
N.A.
42
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
40
N.A.
46.6
N.A.
N.A.
0
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
60
N.A.
66.6
N.A.
N.A.
6.6
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
43
0
15
0
0
0
15
0
0
0
% A
% Cys:
0
0
72
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
0
0
0
0
15
0
0
0
29
0
0
0
% D
% Glu:
0
15
0
0
0
0
0
15
15
0
0
0
0
0
0
% E
% Phe:
0
0
15
0
0
0
72
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
58
15
0
0
0
0
15
0
15
0
0
15
% G
% His:
0
0
0
0
0
0
0
0
15
0
0
29
15
0
0
% H
% Ile:
15
0
0
0
0
0
15
15
0
15
15
15
0
29
29
% I
% Lys:
15
29
0
0
72
0
0
0
0
0
0
0
0
0
15
% K
% Leu:
0
15
0
0
0
15
0
0
15
0
0
0
72
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% M
% Asn:
29
15
0
0
15
0
0
0
15
0
0
0
0
0
0
% N
% Pro:
15
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
15
0
15
0
0
0
0
29
15
0
0
15
0
15
% Q
% Arg:
15
0
0
0
0
15
0
0
15
0
0
0
0
15
0
% R
% Ser:
0
0
0
15
0
15
15
43
0
58
43
0
0
15
0
% S
% Thr:
0
15
0
0
0
15
0
0
0
0
43
0
0
15
15
% T
% Val:
0
0
0
15
0
0
0
0
0
0
0
0
0
15
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _