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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNF594 All Species: 5.76
Human Site: S444 Identified Species: 21.11
UniProt: Q96JF6 Number Species: 6
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96JF6 NP_115919.1 807 93907 S444 C G K S F R G S S D L I R H H
Chimpanzee Pan troglodytes XP_523843 1120 130265 S444 C G K S F R G S S D L I R H H
Rhesus Macaque Macaca mulatta XP_001099720 674 78723 G336 A Y L C N Q C G R N F Q G S S
Dog Lupus familis XP_541659 1259 145674 N834 C G K A F T Q N S Q L T L H Q
Cat Felis silvestris
Mouse Mus musculus Q8C827 914 104793 R479 C G K A Y I S R S S L K N H K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520702 737 83549 S399 Q P S E C G D S G K V Y R H S
Chicken Gallus gallus
Frog Xenopus laevis P08045 1350 155787 R599 C D K S F T E R S A L I K H H
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.8 58.3 38.8 N.A. 40.4 N.A. N.A. 46.7 N.A. 30.6 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 71.5 67.7 47.9 N.A. 56.7 N.A. N.A. 59.9 N.A. 42 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 46.6 N.A. 40 N.A. N.A. 20 N.A. 60 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 60 N.A. 53.3 N.A. N.A. 26.6 N.A. 66.6 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 0 29 0 0 0 0 0 15 0 0 0 0 0 % A
% Cys: 72 0 0 15 15 0 15 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 0 0 0 0 15 0 0 29 0 0 0 0 0 % D
% Glu: 0 0 0 15 0 0 15 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 58 0 0 0 0 0 15 0 0 0 0 % F
% Gly: 0 58 0 0 0 15 29 15 15 0 0 0 15 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 86 43 % H
% Ile: 0 0 0 0 0 15 0 0 0 0 0 43 0 0 0 % I
% Lys: 0 0 72 0 0 0 0 0 0 15 0 15 15 0 15 % K
% Leu: 0 0 15 0 0 0 0 0 0 0 72 0 15 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 15 0 0 15 0 15 0 0 15 0 0 % N
% Pro: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 15 0 0 0 0 15 15 0 0 15 0 15 0 0 15 % Q
% Arg: 0 0 0 0 0 29 0 29 15 0 0 0 43 0 0 % R
% Ser: 0 0 15 43 0 0 15 43 72 15 0 0 0 15 29 % S
% Thr: 0 0 0 0 0 29 0 0 0 0 0 15 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 15 0 0 15 0 0 0 0 0 0 15 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _