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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMX3
All Species:
29.39
Human Site:
S221
Identified Species:
58.79
UniProt:
Q96JJ7
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96JJ7
NP_061895.3
454
51872
S221
Y
E
D
G
D
L
S
S
W
I
N
R
E
R
F
Chimpanzee
Pan troglodytes
XP_001150102
454
51811
S221
Y
E
D
G
D
L
S
S
W
I
N
R
E
R
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533381
524
59421
S292
Y
E
D
G
D
L
S
S
W
I
N
R
E
R
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXZ1
456
51829
S224
Y
E
D
G
D
L
S
S
W
I
S
R
E
R
F
Rat
Rattus norvegicus
XP_001063895
470
53351
S238
Y
E
D
G
D
L
S
S
W
I
S
R
E
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P09102
515
57391
L231
D
L
T
K
D
N
L
L
N
F
I
K
S
N
Q
Frog
Xenopus laevis
Q6GNG3
452
50843
S221
Y
E
D
G
D
L
S
S
W
V
N
K
E
R
F
Zebra Danio
Brachydanio rerio
NP_001039026
484
54109
S214
Y
E
D
G
S
L
S
S
W
V
N
R
E
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
K226
E
L
N
E
E
N
L
K
K
F
A
Q
V
Q
S
Honey Bee
Apis mellifera
XP_001121993
236
27568
S22
V
F
S
G
T
F
T
S
V
I
A
S
R
V
L
Nematode Worm
Caenorhab. elegans
Q17770
493
55134
K222
K
L
T
Q
D
G
L
K
T
W
I
Q
A
N
R
Sea Urchin
Strong. purpuratus
XP_791396
637
72173
Y377
V
Q
D
L
E
N
F
Y
K
E
N
D
V
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
78.2
N.A.
91.6
88.9
N.A.
N.A.
20.5
69.3
58.4
N.A.
21.1
20.4
22.7
21.1
Protein Similarity:
100
99.7
N.A.
83
N.A.
96
93.1
N.A.
N.A.
39.8
83.2
76
N.A.
41.9
32.8
41.7
38.4
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
N.A.
6.6
86.6
86.6
N.A.
0
20
6.6
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
13.3
100
93.3
N.A.
26.6
26.6
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
17
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
67
0
67
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
9
59
0
9
17
0
0
0
0
9
0
0
59
0
0
% E
% Phe:
0
9
0
0
0
9
9
0
0
17
0
0
0
0
59
% F
% Gly:
0
0
0
67
0
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
50
17
0
0
0
0
% I
% Lys:
9
0
0
9
0
0
0
17
17
0
0
17
0
0
0
% K
% Leu:
0
25
0
9
0
59
25
9
0
0
0
0
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
25
0
0
9
0
50
0
0
17
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
9
0
9
0
0
0
0
0
0
0
17
0
9
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
50
9
59
9
% R
% Ser:
0
0
9
0
9
0
59
67
0
0
17
9
9
0
9
% S
% Thr:
0
0
17
0
9
0
9
0
9
0
0
0
0
0
0
% T
% Val:
17
0
0
0
0
0
0
0
9
17
0
0
17
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
59
9
0
0
0
0
0
% W
% Tyr:
59
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _