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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCAF5 All Species: 18.79
Human Site: S559 Identified Species: 37.58
UniProt: Q96JK2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96JK2 NP_003852.1 942 103963 S559 S P S P E D E S S S S S S S S
Chimpanzee Pan troglodytes XP_510028 1219 132740 S836 S P S P E D E S S S S S S S S
Rhesus Macaque Macaca mulatta XP_001104318 1224 133527 S841 S P S P E D E S S S S S S S S
Dog Lupus familis XP_547871 865 95075 R507 R Q R N T M R R R Q K T P R E
Cat Felis silvestris
Mouse Mus musculus Q80T85 946 103657 S559 S P S P E D G S S S P S S S T
Rat Rattus norvegicus NP_001094188 946 103931 S559 S P S P E D G S S S S S S S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426432 942 104366 S541 S S S S S S S S S T E D E E E
Frog Xenopus laevis NP_001090592 936 103775 N557 S D E E N N L N D R R A T M R
Zebra Danio Brachydanio rerio NP_001071020 789 86821 D431 E I E G W S S D S D S D L S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651899 773 87072 Q415 G W E G S L T Q A E A L P Y C
Honey Bee Apis mellifera XP_395601 743 82892 V385 H D E Y I G L V L R S G Q F M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797510 818 90540 A460 P R N G R S N A V K V K P K T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.1 75.9 85.8 N.A. 90.9 91.7 N.A. N.A. 70.6 62.9 53.1 N.A. 30.1 37.4 N.A. 35.1
Protein Similarity: 100 77.1 76 87.7 N.A. 93.7 94.1 N.A. N.A. 76.3 73.8 62.4 N.A. 48.2 51.5 N.A. 52.4
P-Site Identity: 100 100 100 0 N.A. 80 86.6 N.A. N.A. 26.6 6.6 20 N.A. 0 6.6 N.A. 0
P-Site Similarity: 100 100 100 6.6 N.A. 86.6 93.3 N.A. N.A. 33.3 33.3 20 N.A. 13.3 6.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 9 9 0 9 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 17 0 0 0 42 0 9 9 9 0 17 0 0 0 % D
% Glu: 9 0 34 9 42 0 25 0 0 9 9 0 9 9 25 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 9 0 0 25 0 9 17 0 0 0 0 9 0 0 0 % G
% His: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 9 9 9 0 9 0 % K
% Leu: 0 0 0 0 0 9 17 0 9 0 0 9 9 0 0 % L
% Met: 0 0 0 0 0 9 0 0 0 0 0 0 0 9 9 % M
% Asn: 0 0 9 9 9 9 9 9 0 0 0 0 0 0 0 % N
% Pro: 9 42 0 42 0 0 0 0 0 0 9 0 25 0 0 % P
% Gln: 0 9 0 0 0 0 0 9 0 9 0 0 9 0 0 % Q
% Arg: 9 9 9 0 9 0 9 9 9 17 9 0 0 9 9 % R
% Ser: 59 9 50 9 17 25 17 50 59 42 50 42 42 50 25 % S
% Thr: 0 0 0 0 9 0 9 0 0 9 0 9 9 0 25 % T
% Val: 0 0 0 0 0 0 0 9 9 0 9 0 0 0 0 % V
% Trp: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _