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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCAF5 All Species: 20
Human Site: Y617 Identified Species: 40
UniProt: Q96JK2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96JK2 NP_003852.1 942 103963 Y617 I G E D N Y D Y P Q I K V D D
Chimpanzee Pan troglodytes XP_510028 1219 132740 Y894 I G E D N Y D Y P Q I K V D D
Rhesus Macaque Macaca mulatta XP_001104318 1224 133527 Y899 I G E D N Y D Y P Q I K V D D
Dog Lupus familis XP_547871 865 95075 A565 L E I Q P N R A S P T S D I E
Cat Felis silvestris
Mouse Mus musculus Q80T85 946 103657 Y617 I G E D N Y D Y P Q I K V D D
Rat Rattus norvegicus NP_001094188 946 103931 Y617 I G E D N Y D Y P Q I K V D D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426432 942 104366 D599 Y P Q I K V D D L S S S P A S
Frog Xenopus laevis NP_001090592 936 103775 P615 S T S A E S S P E R R S P S G
Zebra Danio Brachydanio rerio NP_001071020 789 86821 S489 A G P D V S G S E R T D Q D R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651899 773 87072 S473 T V D N Q N S S K S S T H T S
Honey Bee Apis mellifera XP_395601 743 82892 A443 D S E S N L I A G R V Y S A T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797510 818 90540 E518 S T S Q A S H E S S E S R R R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.1 75.9 85.8 N.A. 90.9 91.7 N.A. N.A. 70.6 62.9 53.1 N.A. 30.1 37.4 N.A. 35.1
Protein Similarity: 100 77.1 76 87.7 N.A. 93.7 94.1 N.A. N.A. 76.3 73.8 62.4 N.A. 48.2 51.5 N.A. 52.4
P-Site Identity: 100 100 100 0 N.A. 100 100 N.A. N.A. 6.6 0 20 N.A. 0 13.3 N.A. 0
P-Site Similarity: 100 100 100 13.3 N.A. 100 100 N.A. N.A. 13.3 6.6 26.6 N.A. 13.3 26.6 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 9 9 0 0 17 0 0 0 0 0 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 9 50 0 0 50 9 0 0 0 9 9 50 42 % D
% Glu: 0 9 50 0 9 0 0 9 17 0 9 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 50 0 0 0 0 9 0 9 0 0 0 0 0 9 % G
% His: 0 0 0 0 0 0 9 0 0 0 0 0 9 0 0 % H
% Ile: 42 0 9 9 0 0 9 0 0 0 42 0 0 9 0 % I
% Lys: 0 0 0 0 9 0 0 0 9 0 0 42 0 0 0 % K
% Leu: 9 0 0 0 0 9 0 0 9 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 50 17 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 9 9 0 9 0 0 9 42 9 0 0 17 0 0 % P
% Gln: 0 0 9 17 9 0 0 0 0 42 0 0 9 0 0 % Q
% Arg: 0 0 0 0 0 0 9 0 0 25 9 0 9 9 17 % R
% Ser: 17 9 17 9 0 25 17 17 17 25 17 34 9 9 17 % S
% Thr: 9 17 0 0 0 0 0 0 0 0 17 9 0 9 9 % T
% Val: 0 9 0 0 9 9 0 0 0 0 9 0 42 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 42 0 42 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _