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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MS4A4A All Species: 8.18
Human Site: S154 Identified Species: 25.71
UniProt: Q96JQ5 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96JQ5 NP_076926.2 239 25441 S154 G I L I N T F S L A F Y S F H
Chimpanzee Pan troglodytes XP_001138329 239 25461 S154 G I L I N T F S L A F Y S F H
Rhesus Macaque Macaca mulatta XP_001086549 326 35044 S241 A I L I N T I S L A I Y S F Y
Dog Lupus familis XP_534104 436 46753 H345 G V F Y N V I H L D N F K Y N
Cat Felis silvestris
Mouse Mus musculus Q99N05 225 23841 R136 S V I S G V F R Q F R S Q P A
Rat Rattus norvegicus P13386 243 26712 N151 G I A I L I L N L S N N S A Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505337 249 26040 E152 G I L L L I A E L C L N H P R
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001017670 252 26907 L143 A G I A I I M L S V D L A L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 65.6 26.8 N.A. 31.3 29.6 N.A. 26.9 N.A. N.A. 36.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 68.7 37.1 N.A. 46.8 45.6 N.A. 46.1 N.A. N.A. 52.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 73.3 20 N.A. 6.6 33.3 N.A. 26.6 N.A. N.A. 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 80 46.6 N.A. 20 53.3 N.A. 33.3 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 0 13 13 0 0 13 0 0 38 0 0 13 13 13 % A
% Cys: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 13 13 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % E
% Phe: 0 0 13 0 0 0 38 0 0 13 25 13 0 38 0 % F
% Gly: 63 13 0 0 13 0 0 0 0 0 0 0 0 0 13 % G
% His: 0 0 0 0 0 0 0 13 0 0 0 0 13 0 25 % H
% Ile: 0 63 25 50 13 38 25 0 0 0 13 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % K
% Leu: 0 0 50 13 25 0 13 13 75 0 13 13 0 13 0 % L
% Met: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 50 0 0 13 0 0 25 25 0 0 13 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 25 0 % P
% Gln: 0 0 0 0 0 0 0 0 13 0 0 0 13 0 0 % Q
% Arg: 0 0 0 0 0 0 0 13 0 0 13 0 0 0 13 % R
% Ser: 13 0 0 13 0 0 0 38 13 13 0 13 50 0 0 % S
% Thr: 0 0 0 0 0 38 0 0 0 0 0 0 0 0 0 % T
% Val: 0 25 0 0 0 25 0 0 0 13 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 13 0 0 0 0 0 0 0 38 0 13 25 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _