Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF170 All Species: 10
Human Site: S146 Identified Species: 24.44
UniProt: Q96K19 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96K19 NP_001153695.1 258 29815 S146 V F G E D D Q S Q D V L R L H
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532788 302 34426 S190 V F G E N D Q S Q D V V S L R
Cat Felis silvestris
Mouse Mus musculus Q8CBG9 286 33395 S174 V F G E D D Q S Q D V I R L R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509677 293 33361 P181 L F G E V S Q P Q D G A Q L H
Chicken Gallus gallus NP_001171208 256 29611 G146 L F S E D Q Q G A T Q V L Q D
Frog Xenopus laevis Q5PPX5 257 29466 E146 L F G A T D Q E D A Q N I L Q
Zebra Danio Brachydanio rerio Q7SZN2 266 29609 S147 L F Q D S E Q S A V A A D S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496760 283 32692 G164 P V H W P T M G T S E E T D D
Sea Urchin Strong. purpuratus XP_783372 283 31668 N171 V F Q E D E Q N S G E G G R I
Poplar Tree Populus trichocarpa XP_002325966 185 20672 G94 L F G G N T S G L I Q R M Q D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 82.7 N.A. 81.8 N.A. N.A. 77.8 81 72 63.5 N.A. N.A. N.A. 28.6 42.4
Protein Similarity: 100 N.A. N.A. 83.4 N.A. 85.6 N.A. N.A. 80.5 87.2 83.3 76.3 N.A. N.A. N.A. 47 59.7
P-Site Identity: 100 N.A. N.A. 73.3 N.A. 86.6 N.A. N.A. 53.3 26.6 33.3 20 N.A. N.A. N.A. 0 33.3
P-Site Similarity: 100 N.A. N.A. 86.6 N.A. 93.3 N.A. N.A. 66.6 40 40 40 N.A. N.A. N.A. 0 46.6
Percent
Protein Identity: 26.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 41 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 26.6 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 20 10 10 20 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 40 40 0 0 10 40 0 0 10 10 30 % D
% Glu: 0 0 0 60 0 20 0 10 0 0 20 10 0 0 0 % E
% Phe: 0 90 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 60 10 0 0 0 30 0 10 10 10 10 0 0 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 20 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 0 10 10 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 50 0 0 0 0 0 0 0 10 0 0 10 10 50 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 20 0 0 10 0 0 0 10 0 0 0 % N
% Pro: 10 0 0 0 10 0 0 10 0 0 0 0 0 0 10 % P
% Gln: 0 0 20 0 0 10 80 0 40 0 30 0 10 20 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 10 20 10 20 % R
% Ser: 0 0 10 0 10 10 10 40 10 10 0 0 10 10 0 % S
% Thr: 0 0 0 0 10 20 0 0 10 10 0 0 10 0 0 % T
% Val: 40 10 0 0 10 0 0 0 0 10 30 20 0 0 0 % V
% Trp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _