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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF170 All Species: 16.06
Human Site: T69 Identified Species: 39.26
UniProt: Q96K19 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96K19 NP_001153695.1 258 29815 T69 V L R E Q L Q T E Q D A P A A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532788 302 34426 T113 V L R E Q L Q T E Q D A P A A
Cat Felis silvestris
Mouse Mus musculus Q8CBG9 286 33395 T97 V L R E Q F Q T E Q D V P A P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509677 293 33361 T104 V L R E Q L Q T E Q D E P V V
Chicken Gallus gallus NP_001171208 256 29611 T69 A L R Q Q L Q T E Q D A S T G
Frog Xenopus laevis Q5PPX5 257 29466 N69 A V R E Q L Q N E Q E T P A P
Zebra Danio Brachydanio rerio Q7SZN2 266 29609 Q70 R V V R E Q L Q A E Q V S S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496760 283 32692 Q87 D E N A E R N Q I I T Q R R I
Sea Urchin Strong. purpuratus XP_783372 283 31668 S94 Q Q N G E G Q S S D G R H G M
Poplar Tree Populus trichocarpa XP_002325966 185 20672 F17 C S I C H G H F N I A C Q A N
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 82.7 N.A. 81.8 N.A. N.A. 77.8 81 72 63.5 N.A. N.A. N.A. 28.6 42.4
Protein Similarity: 100 N.A. N.A. 83.4 N.A. 85.6 N.A. N.A. 80.5 87.2 83.3 76.3 N.A. N.A. N.A. 47 59.7
P-Site Identity: 100 N.A. N.A. 100 N.A. 80 N.A. N.A. 80 66.6 60 0 N.A. N.A. N.A. 0 6.6
P-Site Similarity: 100 N.A. N.A. 100 N.A. 80 N.A. N.A. 80 73.3 73.3 26.6 N.A. N.A. N.A. 6.6 20
Percent
Protein Identity: 26.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 41 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 6.6 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 0 10 0 0 0 0 10 0 10 30 0 50 20 % A
% Cys: 10 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 10 50 0 0 0 0 % D
% Glu: 0 10 0 50 30 0 0 0 60 10 10 10 0 0 10 % E
% Phe: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 20 0 0 0 0 10 0 0 10 10 % G
% His: 0 0 0 0 10 0 10 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 10 20 0 0 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 50 0 0 0 50 10 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 20 0 0 0 10 10 10 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 50 0 20 % P
% Gln: 10 10 0 10 60 10 70 20 0 60 10 10 10 0 0 % Q
% Arg: 10 0 60 10 0 10 0 0 0 0 0 10 10 10 0 % R
% Ser: 0 10 0 0 0 0 0 10 10 0 0 0 20 10 0 % S
% Thr: 0 0 0 0 0 0 0 50 0 0 10 10 0 10 0 % T
% Val: 40 20 10 0 0 0 0 0 0 0 0 20 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _