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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZFYVE19 All Species: 5.76
Human Site: S216 Identified Species: 14.07
UniProt: Q96K21 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96K21 NP_001070736.1 471 51530 S216 E R Q G S I P S T Q E M E A R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001098626 398 43950 A189 Q D L L T Q L A A E V A I D S
Dog Lupus familis XP_544623 399 43793 V190 L T Q L A A E V A I D E S S E
Cat Felis silvestris
Mouse Mus musculus Q9DAZ9 389 43258 D180 T Q A Q Q T Q D L L T Q L T A
Rat Rattus norvegicus NP_001030120 386 43010 Q177 D T R T Q A Q Q T Q D L L T Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518683 239 25895 A30 L E A R R G P A A S R P A A Q
Chicken Gallus gallus XP_421128 399 44352 S190 P P D T R S L S Q Q T D D L L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002412 431 48047 S211 A A I D N Q N S S S D V D A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573077 342 38590 S133 H I D E N L D S E L T K R M Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796605 418 46896 T205 R L E G N D V T P N G G S S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 78.1 72.4 N.A. 66.8 63.9 N.A. 32.2 44.1 N.A. 39.2 N.A. 23.3 N.A. N.A. 27.8
Protein Similarity: 100 N.A. 81.3 77 N.A. 72.4 70.4 N.A. 38.6 57.1 N.A. 57.1 N.A. 35 N.A. N.A. 41.4
P-Site Identity: 100 N.A. 0 6.6 N.A. 0 13.3 N.A. 13.3 13.3 N.A. 13.3 N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 N.A. 26.6 26.6 N.A. 6.6 46.6 N.A. 26.6 20 N.A. 46.6 N.A. 26.6 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 20 0 10 20 0 20 30 0 0 10 10 30 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 10 20 10 0 10 10 10 0 0 30 10 20 10 0 % D
% Glu: 10 10 10 10 0 0 10 0 10 10 10 10 10 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 20 0 10 0 0 0 0 10 10 0 0 10 % G
% His: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 10 0 0 10 0 0 0 10 0 0 10 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % K
% Leu: 20 10 10 20 0 10 20 0 10 20 0 10 20 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % M
% Asn: 0 0 0 0 30 0 10 0 0 10 0 0 0 0 0 % N
% Pro: 10 10 0 0 0 0 20 0 10 0 0 10 0 0 0 % P
% Gln: 10 10 20 10 20 20 20 10 10 30 0 10 0 0 30 % Q
% Arg: 10 10 10 10 20 0 0 0 0 0 10 0 10 0 10 % R
% Ser: 0 0 0 0 10 10 0 40 10 20 0 0 20 20 20 % S
% Thr: 10 20 0 20 10 10 0 10 20 0 30 0 0 20 0 % T
% Val: 0 0 0 0 0 0 10 10 0 0 10 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _