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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE19
All Species:
0.61
Human Site:
T236
Identified Species:
1.48
UniProt:
Q96K21
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96K21
NP_001070736.1
471
51530
T236
G
R
V
L
P
S
Q
T
P
Q
P
A
H
H
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001098626
398
43950
Q207
G
D
P
A
A
S
L
Q
N
D
L
N
Q
G
G
Dog
Lupus familis
XP_544623
399
43793
D208
P
A
A
S
I
Q
N
D
L
N
R
G
G
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9DAZ9
389
43258
R198
I
D
E
N
C
Q
P
R
A
S
A
S
L
Q
N
Rat
Rattus norvegicus
NP_001030120
386
43010
W195
E
V
A
I
D
E
N
W
Q
P
R
V
S
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518683
239
25895
L48
D
Q
V
I
A
Q
R
L
E
R
L
R
Q
E
S
Chicken
Gallus gallus
XP_421128
399
44352
E208
A
E
E
V
S
I
D
E
H
Y
S
P
G
V
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002412
431
48047
S229
N
D
L
N
K
Q
A
S
V
N
E
N
V
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573077
342
38590
E151
R
V
D
A
T
D
D
E
I
R
T
R
L
A
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796605
418
46896
P225
S
G
D
N
D
H
R
P
P
G
G
R
G
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
78.1
72.4
N.A.
66.8
63.9
N.A.
32.2
44.1
N.A.
39.2
N.A.
23.3
N.A.
N.A.
27.8
Protein Similarity:
100
N.A.
81.3
77
N.A.
72.4
70.4
N.A.
38.6
57.1
N.A.
57.1
N.A.
35
N.A.
N.A.
41.4
P-Site Identity:
100
N.A.
13.3
0
N.A.
0
0
N.A.
6.6
0
N.A.
0
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
13.3
0
N.A.
6.6
6.6
N.A.
40
6.6
N.A.
13.3
N.A.
6.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
20
20
20
0
10
0
10
0
10
10
0
20
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
30
20
0
20
10
20
10
0
10
0
0
0
10
20
% D
% Glu:
10
10
20
0
0
10
0
20
10
0
10
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
20
10
0
0
0
0
0
0
0
10
10
10
30
10
20
% G
% His:
0
0
0
0
0
10
0
0
10
0
0
0
10
10
0
% H
% Ile:
10
0
0
20
10
10
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
10
0
0
10
10
10
0
20
0
20
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
30
0
0
20
0
10
20
0
20
0
0
20
% N
% Pro:
10
0
10
0
10
0
10
10
20
10
10
10
0
10
10
% P
% Gln:
0
10
0
0
0
40
10
10
10
10
0
0
20
10
10
% Q
% Arg:
10
10
0
0
0
0
20
10
0
20
20
30
0
10
0
% R
% Ser:
10
0
0
10
10
20
0
10
0
10
10
10
10
0
10
% S
% Thr:
0
0
0
0
10
0
0
10
0
0
10
0
0
0
10
% T
% Val:
0
20
20
10
0
0
0
0
10
0
0
10
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _