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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CLPTM1L All Species: 30.61
Human Site: S317 Identified Species: 67.33
UniProt: Q96KA5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96KA5 NP_110409.2 538 62229 S317 S F W K K K K S M I G M S T K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001097234 538 62159 S317 S F W K K K K S M I G M S T K
Dog Lupus familis XP_535803 539 62409 S318 S F W K K K K S M I G M S T K
Cat Felis silvestris
Mouse Mus musculus Q8BXA5 539 62165 S318 S F W K K K K S M I G M S T K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506351 508 59149 V296 I G M S T K A V L W R C F S T
Chicken Gallus gallus Q5ZKJ0 536 61630 S317 S F W K K K R S M I G M S T K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6DHU1 538 62478 S317 S F W K H K K S M V G M S S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122306 515 60039 N296 S Y W R R K D N L V G L S K W
Nematode Worm Caenorhab. elegans NP_495797 566 65494 S322 S F W K G R K S M V G L S T K
Sea Urchin Strong. purpuratus XP_783712 533 61293 S311 L I Y F V H A S W S S F V S S
Poplar Tree Populus trichocarpa XP_002325290 557 64464 S325 Q F W N K N K S M E G L S A K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99 94.9 N.A. 92.7 N.A. N.A. 84.7 89.5 N.A. 73.9 N.A. N.A. 47 42.4 47.2
Protein Similarity: 100 N.A. 99.4 97.2 N.A. 96.6 N.A. N.A. 89.9 94.9 N.A. 86.6 N.A. N.A. 65.6 62.3 67.2
P-Site Identity: 100 N.A. 100 100 N.A. 100 N.A. N.A. 6.6 93.3 N.A. 80 N.A. N.A. 33.3 73.3 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 N.A. N.A. 20 100 N.A. 93.3 N.A. N.A. 80 93.3 20
Percent
Protein Identity: 35.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 57.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 60 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 66.6 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 19 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % E
% Phe: 0 73 0 10 0 0 0 0 0 0 0 10 10 0 0 % F
% Gly: 0 10 0 0 10 0 0 0 0 0 82 0 0 0 0 % G
% His: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 10 0 0 0 0 0 0 0 46 0 0 0 0 0 % I
% Lys: 0 0 0 64 55 73 64 0 0 0 0 0 0 10 73 % K
% Leu: 10 0 0 0 0 0 0 0 19 0 0 28 0 0 0 % L
% Met: 0 0 10 0 0 0 0 0 73 0 0 55 0 0 0 % M
% Asn: 0 0 0 10 0 10 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 10 10 10 10 0 0 0 10 0 0 0 0 % R
% Ser: 73 0 0 10 0 0 0 82 0 10 10 0 82 28 10 % S
% Thr: 0 0 0 0 10 0 0 0 0 0 0 0 0 55 10 % T
% Val: 0 0 0 0 10 0 0 10 0 28 0 0 10 0 0 % V
% Trp: 0 0 82 0 0 0 0 0 10 10 0 0 0 0 10 % W
% Tyr: 0 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _