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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLPTM1L
All Species:
22.42
Human Site:
S389
Identified Species:
49.33
UniProt:
Q96KA5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96KA5
NP_110409.2
538
62229
S389
Q
F
G
T
Y
S
E
S
E
R
K
T
E
E
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097234
538
62159
S389
Q
F
G
T
Y
S
E
S
E
R
K
T
E
E
Y
Dog
Lupus familis
XP_535803
539
62409
S390
Q
F
G
T
Y
S
E
S
E
R
K
T
E
E
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXA5
539
62165
S390
Q
F
G
T
H
S
E
S
E
R
K
T
E
K
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506351
508
59149
S359
Q
F
G
A
Y
N
E
S
E
R
K
T
E
E
Y
Chicken
Gallus gallus
Q5ZKJ0
536
61630
S386
P
K
V
Q
F
G
A
S
N
D
S
E
K
K
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DHU1
538
62478
S389
L
F
G
K
L
D
E
S
E
K
R
T
E
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122306
515
60039
A363
N
N
N
N
N
Y
M
A
E
I
R
T
R
E
F
Nematode Worm
Caenorhab. elegans
NP_495797
566
65494
E390
K
F
G
K
H
S
T
E
E
D
E
T
D
S
I
Sea Urchin
Strong. purpuratus
XP_783712
533
61293
E382
C
G
I
G
A
L
I
E
V
W
K
V
K
K
A
Poplar Tree
Populus trichocarpa
XP_002325290
557
64464
A398
F
R
D
R
E
S
Y
A
G
N
K
T
K
E
Y
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99
94.9
N.A.
92.7
N.A.
N.A.
84.7
89.5
N.A.
73.9
N.A.
N.A.
47
42.4
47.2
Protein Similarity:
100
N.A.
99.4
97.2
N.A.
96.6
N.A.
N.A.
89.9
94.9
N.A.
86.6
N.A.
N.A.
65.6
62.3
67.2
P-Site Identity:
100
N.A.
100
100
N.A.
86.6
N.A.
N.A.
86.6
6.6
N.A.
60
N.A.
N.A.
20
33.3
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
93.3
26.6
N.A.
73.3
N.A.
N.A.
40
60
20
Percent
Protein Identity:
35.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
57.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
0
10
19
0
0
0
0
0
0
10
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
10
0
0
0
19
0
0
10
0
0
% D
% Glu:
0
0
0
0
10
0
55
19
73
0
10
10
55
64
0
% E
% Phe:
10
64
0
0
10
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
10
64
10
0
10
0
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
10
0
0
10
0
0
0
0
10
% I
% Lys:
10
10
0
19
0
0
0
0
0
10
64
0
28
28
0
% K
% Leu:
10
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
10
10
10
10
0
0
10
10
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
46
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
10
0
0
0
0
0
46
19
0
10
0
0
% R
% Ser:
0
0
0
0
0
55
0
64
0
0
10
0
0
10
0
% S
% Thr:
0
0
0
37
0
0
10
0
0
0
0
82
0
0
10
% T
% Val:
0
0
10
0
0
0
0
0
10
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
37
10
10
0
0
0
0
0
0
0
64
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _