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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PBK All Species: 27.58
Human Site: S52 Identified Species: 46.67
UniProt: Q96KB5 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96KB5 NP_060962.2 322 36085 S52 N V Y L M K R S P R G L S H S
Chimpanzee Pan troglodytes XP_520045 322 36011 S52 N V Y L M K R S P R G L S H S
Rhesus Macaque Macaca mulatta XP_001109768 323 36123 S52 N V Y L M K R S P R G L S H S
Dog Lupus familis XP_534564 324 36430 S52 N V Y L M K R S P R G L S H S
Cat Felis silvestris
Mouse Mus musculus Q9JJ78 330 36726 P52 V Y L M K R S P R G L S H S P
Rat Rattus norvegicus NP_001073406 337 37551 S52 S V Y L M K R S P R G L S H S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508951 321 35996 S52 N V Y L M K R S P K G L S Q S
Chicken Gallus gallus XP_420011 322 35395 R52 R S P R G L S R S P W A V K K
Frog Xenopus laevis NP_001088960 325 36517 S53 S V Y L M K R S P K G L S H S
Zebra Danio Brachydanio rerio Q6DHU8 339 37645 R55 V N V Y L M N R M G K Q T H S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573239 398 44994 R55 S P R L G E I R S P W A V K R
Honey Bee Apis mellifera XP_623765 343 38973 P52 V F S L E R S P K V G F I R S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798752 344 37735 R73 Y L L E R S P R P D G S G R S
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001130276 278 30401 Y17 R G S V G T T Y K A V L D G R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 96.5 93.5 N.A. 85.4 86.3 N.A. 83.2 73.5 70.1 64 N.A. 35.9 41.4 N.A. 46.5
Protein Similarity: 100 99.6 98.7 96.9 N.A. 92.4 91.9 N.A. 89.7 85.4 85.2 77.2 N.A. 51.2 58.8 N.A. 63.9
P-Site Identity: 100 100 100 100 N.A. 0 93.3 N.A. 86.6 0 86.6 13.3 N.A. 6.6 20 N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 13.3 100 N.A. 93.3 0 100 26.6 N.A. 20 26.6 N.A. 26.6
Percent
Protein Identity: N.A. 26.7 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 45.6 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 13.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 8 0 15 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % D
% Glu: 0 0 0 8 8 8 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 8 0 0 22 0 0 0 0 15 65 0 8 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 50 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 0 % I
% Lys: 0 0 0 0 8 50 0 0 15 15 8 0 0 15 8 % K
% Leu: 0 8 15 65 8 8 0 0 0 0 8 58 0 0 0 % L
% Met: 0 0 0 8 50 8 0 0 8 0 0 0 0 0 0 % M
% Asn: 36 8 0 0 0 0 8 0 0 0 0 0 0 0 0 % N
% Pro: 0 8 8 0 0 0 8 15 58 15 0 0 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % Q
% Arg: 15 0 8 8 8 15 50 29 8 36 0 0 0 15 15 % R
% Ser: 22 8 15 0 0 8 22 50 15 0 0 15 50 8 72 % S
% Thr: 0 0 0 0 0 8 8 0 0 0 0 0 8 0 0 % T
% Val: 22 50 8 8 0 0 0 0 0 8 8 0 15 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % W
% Tyr: 8 8 50 8 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _