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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PBK All Species: 26.67
Human Site: T104 Identified Species: 45.13
UniProt: Q96KB5 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96KB5 NP_060962.2 322 36085 T104 I V G Y R A F T E A N D G S L
Chimpanzee Pan troglodytes XP_520045 322 36011 T104 I V G Y R A F T E A S D G S L
Rhesus Macaque Macaca mulatta XP_001109768 323 36123 T104 I V G Y R A F T E A S D G S L
Dog Lupus familis XP_534564 324 36430 T104 I V G Y R A F T E A S D G S L
Cat Felis silvestris
Mouse Mus musculus Q9JJ78 330 36726 E104 I G Y R A F T E A S D G S L C
Rat Rattus norvegicus NP_001073406 337 37551 T104 I V G Y R A F T E A S D G S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508951 321 35996 T104 I V G Y R A F T E A H D G S M
Chicken Gallus gallus XP_420011 322 35395 S104 F T E A N D G S M C L V M E F
Frog Xenopus laevis NP_001088960 325 36517 A105 I V G Y R A F A K S K D G S L
Zebra Danio Brachydanio rerio Q6DHU8 339 37645 T107 I V G F R A F T T A K D G S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573239 398 44994 I107 V I T N D E G I N T L A L E M
Honey Bee Apis mellifera XP_623765 343 38973 L104 G F R A F S K L P N G E P C L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798752 344 37735 L125 N I V E F R A L S K S A D G S
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001130276 278 30401 F69 L V P L R A F F Q A K E E R L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 96.5 93.5 N.A. 85.4 86.3 N.A. 83.2 73.5 70.1 64 N.A. 35.9 41.4 N.A. 46.5
Protein Similarity: 100 99.6 98.7 96.9 N.A. 92.4 91.9 N.A. 89.7 85.4 85.2 77.2 N.A. 51.2 58.8 N.A. 63.9
P-Site Identity: 100 93.3 93.3 93.3 N.A. 6.6 93.3 N.A. 86.6 0 73.3 73.3 N.A. 0 6.6 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 20 100 N.A. 100 6.6 86.6 80 N.A. 20 20 N.A. 13.3
Percent
Protein Identity: N.A. 26.7 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 45.6 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 40 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 60 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 15 8 65 8 8 8 58 0 15 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 8 % C
% Asp: 0 0 0 0 8 8 0 0 0 0 8 58 8 0 0 % D
% Glu: 0 0 8 8 0 8 0 8 43 0 0 15 8 15 0 % E
% Phe: 8 8 0 8 15 8 65 8 0 0 0 0 0 0 8 % F
% Gly: 8 8 58 0 0 0 15 0 0 0 8 8 58 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 65 15 0 0 0 0 0 8 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 8 0 8 8 22 0 0 0 8 % K
% Leu: 8 0 0 8 0 0 0 15 0 0 15 0 8 8 58 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 15 % M
% Asn: 8 0 0 8 8 0 0 0 8 8 8 0 0 0 0 % N
% Pro: 0 0 8 0 0 0 0 0 8 0 0 0 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Q
% Arg: 0 0 8 8 65 8 0 0 0 0 0 0 0 8 0 % R
% Ser: 0 0 0 0 0 8 0 8 8 15 36 0 8 58 8 % S
% Thr: 0 8 8 0 0 0 8 50 8 8 0 0 0 0 0 % T
% Val: 8 65 8 0 0 0 0 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 50 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _