Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARL5B All Species: 33.64
Human Site: S145 Identified Species: 49.33
UniProt: Q96KC2 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96KC2 NP_848930.1 179 20375 S145 I S K Y L T L S S I K D H P W
Chimpanzee Pan troglodytes XP_001136344 320 35436 T286 I S Q F L K L T S I K D H Q W
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_851644 179 20096 S145 I S Q F L T L S A I K D H P W
Cat Felis silvestris
Mouse Mus musculus Q80ZU0 179 20705 T145 I S Q F L K L T S I K D H Q W
Rat Rattus norvegicus P51646 179 20695 T145 I S Q F L K L T S I K D H Q W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510998 179 20324 S145 I S K S L T L S S I K D H P W
Chicken Gallus gallus P26990 175 20078 T142 I Q E K L G L T R I R D R N W
Frog Xenopus laevis P51643 181 20696 H146 I T D K L G L H S L R H R N W
Zebra Danio Brachydanio rerio NP_956118 179 20470 S145 I Y K Y L T L S S I K D H P W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P61209 182 20669 H146 I T D K L G L H S L R N R N W
Honey Bee Apis mellifera XP_623433 179 20512 T145 I S R Q L D L T S I K K H Q W
Nematode Worm Caenorhab. elegans P34212 178 20015 L143 P A E V S T Q L G L Q T L R G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P49076 181 20642 N146 I T D K L G L N S L R Q R H W
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SRC3 181 20574 H146 I T D K L G L H S L R Q R H W
Baker's Yeast Sacchar. cerevisiae P11076 181 20511 H146 I T E K L G L H S I R N R P W
Red Bread Mold Neurospora crassa Q7RVM2 185 20961 S149 I T D K L G L S S L R Q R S W
Conservation
Percent
Protein Identity: 100 46.2 N.A. 76.5 N.A. 79.8 80.4 N.A. 95.5 43.5 48.6 94.9 N.A. 49.4 73.7 52.5 N.A.
Protein Similarity: 100 52.5 N.A. 87.1 N.A. 91.6 92.1 N.A. 98.3 65.9 70.7 97.2 N.A. 70.8 88.2 72 N.A.
P-Site Identity: 100 66.6 N.A. 80 N.A. 66.6 66.6 N.A. 93.3 40 33.3 93.3 N.A. 33.3 60 6.6 N.A.
P-Site Similarity: 100 86.6 N.A. 100 N.A. 86.6 86.6 N.A. 93.3 60 53.3 93.3 N.A. 60 73.3 33.3 N.A.
Percent
Protein Identity: N.A. 50.8 N.A. 50.2 51.3 49.7
Protein Similarity: N.A. 71.2 N.A. 71.2 71.2 69.1
P-Site Identity: N.A. 33.3 N.A. 33.3 46.6 40
P-Site Similarity: N.A. 60 N.A. 53.3 73.3 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 0 0 7 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 32 0 0 7 0 0 0 0 0 50 0 0 0 % D
% Glu: 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 25 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 44 0 0 7 0 0 0 0 0 7 % G
% His: 0 0 0 0 0 0 0 25 0 0 0 7 50 13 0 % H
% Ile: 94 0 0 0 0 0 0 0 0 63 0 0 0 0 0 % I
% Lys: 0 0 19 44 0 19 0 0 0 0 50 7 0 0 0 % K
% Leu: 0 0 0 0 94 0 94 7 0 38 0 0 7 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 7 0 0 0 13 0 19 0 % N
% Pro: 7 0 0 0 0 0 0 0 0 0 0 0 0 32 0 % P
% Gln: 0 7 25 7 0 0 7 0 0 0 7 19 0 25 0 % Q
% Arg: 0 0 7 0 0 0 0 0 7 0 44 0 44 7 0 % R
% Ser: 0 44 0 7 7 0 0 32 82 0 0 0 0 7 0 % S
% Thr: 0 38 0 0 0 32 0 32 0 0 0 7 0 0 0 % T
% Val: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94 % W
% Tyr: 0 7 0 13 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _