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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARL5B All Species: 31.82
Human Site: S45 Identified Species: 46.67
UniProt: Q96KC2 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96KC2 NP_848930.1 179 20375 S45 M N E V V H T S P T I G S N V
Chimpanzee Pan troglodytes XP_001136344 320 35436 S186 M N E V V H T S P T I G S N V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_851644 179 20096 S45 M N E V I H T S P T I G S N V
Cat Felis silvestris
Mouse Mus musculus Q80ZU0 179 20705 S45 M N E V V H T S P T I G S N V
Rat Rattus norvegicus P51646 179 20695 S45 M N E V V H T S P T I G S N V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510998 179 20324 S45 M N E V V H T S P T I G S N V
Chicken Gallus gallus P26990 175 20078 I42 L G Q S V T T I P T V G F N V
Frog Xenopus laevis P51643 181 20696 I46 L G E I V T T I P T I G F N V
Zebra Danio Brachydanio rerio NP_956118 179 20470 S45 M N E V V H T S P T I G S N V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P61209 182 20669 I46 L G E I V T T I P T I G F N V
Honey Bee Apis mellifera XP_623433 179 20512 S45 M N E V V H T S P T I G S N V
Nematode Worm Caenorhab. elegans P34212 178 20015 K46 T K D Q V E T K P T I G S N V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P49076 181 20642 I46 L G E I V T T I P T I G F N V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SRC3 181 20574 I46 L G E I V T T I P T I G F N V
Baker's Yeast Sacchar. cerevisiae P11076 181 20511 I46 L G E V I T T I P T I G F N V
Red Bread Mold Neurospora crassa Q7RVM2 185 20961 I49 L G E V V T T I P T I G F N V
Conservation
Percent
Protein Identity: 100 46.2 N.A. 76.5 N.A. 79.8 80.4 N.A. 95.5 43.5 48.6 94.9 N.A. 49.4 73.7 52.5 N.A.
Protein Similarity: 100 52.5 N.A. 87.1 N.A. 91.6 92.1 N.A. 98.3 65.9 70.7 97.2 N.A. 70.8 88.2 72 N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 100 100 N.A. 100 46.6 60 100 N.A. 60 100 60 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 66.6 73.3 100 N.A. 73.3 100 66.6 N.A.
Percent
Protein Identity: N.A. 50.8 N.A. 50.2 51.3 49.7
Protein Similarity: N.A. 71.2 N.A. 71.2 71.2 69.1
P-Site Identity: N.A. 60 N.A. 60 60 66.6
P-Site Similarity: N.A. 73.3 N.A. 73.3 73.3 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 88 0 0 7 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 44 0 0 % F
% Gly: 0 44 0 0 0 0 0 0 0 0 0 100 0 0 0 % G
% His: 0 0 0 0 0 50 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 25 13 0 0 44 0 0 94 0 0 0 0 % I
% Lys: 0 7 0 0 0 0 0 7 0 0 0 0 0 0 0 % K
% Leu: 44 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 50 0 0 0 0 0 0 0 0 0 0 0 100 0 % N
% Pro: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % P
% Gln: 0 0 7 7 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 7 0 0 0 50 0 0 0 0 57 0 0 % S
% Thr: 7 0 0 0 0 44 100 0 0 100 0 0 0 0 0 % T
% Val: 0 0 0 63 88 0 0 0 0 0 7 0 0 0 100 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _