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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEGF10 All Species: 12.42
Human Site: S1014 Identified Species: 22.78
UniProt: Q96KG7 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96KG7 NP_115822.1 1140 122205 S1014 L K D L G K N S E Y N S S N C
Chimpanzee Pan troglodytes XP_517907 1140 122173 S1014 L K D L G K N S E Y N S S N C
Rhesus Macaque Macaca mulatta XP_001097941 1137 121871 L1007 R S Y M G K S L K D L G K N S
Dog Lupus familis XP_531893 1548 166681 L1418 R S Y M G K S L K D L G K N S
Cat Felis silvestris
Mouse Mus musculus Q6DIB5 1147 122953 S1014 L K D L G K N S E Y N S S T C
Rat Rattus norvegicus O88281 1574 165428 Q1441 C Q R V C E C Q Q G A P C D P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507076 1158 124996 S1027 S L K D L K H S E Y N S S S C
Chicken Gallus gallus XP_424719 1278 138126 K1153 L D R G Y L G K S L K D L V K
Frog Xenopus laevis P21783 2524 275106 S2385 Q N L Q L H Q S M Q Q Q H H N
Zebra Danio Brachydanio rerio P46530 2437 262289 A2019 V D D S G K S A L H W A A A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728660 1031 112996 N906 G S Y S I N Y N H D L L T K N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XWD6 1111 118785 F977 V F P D S D A F S S E N N G N
Sea Urchin Strong. purpuratus P10079 1064 112055 C939 N C E E V G F C D L E G M W Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98.9 70.3 N.A. 94.3 27.5 N.A. 85.3 79.5 21.5 21.5 N.A. 35.2 N.A. 30.9 22.5
Protein Similarity: 100 99.6 99.4 72 N.A. 96.5 37 N.A. 91.2 83.9 29.6 30 N.A. 48.5 N.A. 46.9 36.6
P-Site Identity: 100 100 20 20 N.A. 93.3 0 N.A. 53.3 6.6 6.6 20 N.A. 0 N.A. 0 0
P-Site Similarity: 100 100 40 40 N.A. 93.3 33.3 N.A. 66.6 6.6 13.3 60 N.A. 13.3 N.A. 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 8 0 0 8 8 8 8 0 % A
% Cys: 8 8 0 0 8 0 8 8 0 0 0 0 8 0 31 % C
% Asp: 0 16 31 16 0 8 0 0 8 24 0 8 0 8 0 % D
% Glu: 0 0 8 8 0 8 0 0 31 0 16 0 0 0 0 % E
% Phe: 0 8 0 0 0 0 8 8 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 8 47 8 8 0 0 8 0 24 0 8 0 % G
% His: 0 0 0 0 0 8 8 0 8 8 0 0 8 8 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 24 8 0 0 54 0 8 16 0 8 0 16 8 8 % K
% Leu: 31 8 8 24 16 8 0 16 8 16 24 8 8 0 0 % L
% Met: 0 0 0 16 0 0 0 0 8 0 0 0 8 0 0 % M
% Asn: 8 8 0 0 0 8 24 8 0 0 31 8 8 31 24 % N
% Pro: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 8 % P
% Gln: 8 8 0 8 0 0 8 8 8 8 8 8 0 0 0 % Q
% Arg: 16 0 16 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 24 0 16 8 0 24 39 16 8 0 31 31 8 16 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % T
% Val: 16 0 0 8 8 0 0 0 0 0 0 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % W
% Tyr: 0 0 24 0 8 0 8 0 0 31 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _