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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEGF10
All Species:
16.06
Human Site:
S1059
Identified Species:
29.44
UniProt:
Q96KG7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96KG7
NP_115822.1
1140
122205
S1059
K
S
P
A
R
R
D
S
P
Y
A
E
I
N
N
Chimpanzee
Pan troglodytes
XP_517907
1140
122173
S1059
K
S
P
A
R
R
D
S
P
Y
A
E
I
N
N
Rhesus Macaque
Macaca mulatta
XP_001097941
1137
121871
K1052
E
C
G
Y
V
E
M
K
S
P
A
R
R
D
S
Dog
Lupus familis
XP_531893
1548
166681
K1463
E
C
G
Y
V
E
M
K
S
P
A
R
R
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6DIB5
1147
122953
S1059
K
S
P
A
R
R
D
S
P
Y
A
E
I
N
N
Rat
Rattus norvegicus
O88281
1574
165428
G1486
Q
Q
C
N
C
H
T
G
V
P
C
D
P
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507076
1158
124996
Y1072
K
S
P
A
R
R
D
Y
P
Y
T
E
I
S
S
Chicken
Gallus gallus
XP_424719
1278
138126
E1198
S
S
E
C
G
Y
V
E
M
K
S
P
V
R
R
Frog
Xenopus laevis
P21783
2524
275106
T2430
H
S
V
M
P
Q
D
T
Q
I
F
A
A
S
L
Zebra Danio
Brachydanio rerio
P46530
2437
262289
T2064
A
R
E
G
S
Y
E
T
A
K
V
L
L
D
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728660
1031
112996
H951
K
D
P
D
E
Y
D
H
L
D
Y
S
R
P
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XWD6
1111
118785
L1022
G
N
N
D
Y
A
S
L
D
E
V
A
G
E
G
Sea Urchin
Strong. purpuratus
P10079
1064
112055
V984
Y
A
A
P
T
V
V
V
G
Y
A
S
N
N
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.9
70.3
N.A.
94.3
27.5
N.A.
85.3
79.5
21.5
21.5
N.A.
35.2
N.A.
30.9
22.5
Protein Similarity:
100
99.6
99.4
72
N.A.
96.5
37
N.A.
91.2
83.9
29.6
30
N.A.
48.5
N.A.
46.9
36.6
P-Site Identity:
100
100
6.6
6.6
N.A.
100
0
N.A.
73.3
6.6
13.3
0
N.A.
20
N.A.
0
20
P-Site Similarity:
100
100
26.6
26.6
N.A.
100
20
N.A.
86.6
20
33.3
33.3
N.A.
26.6
N.A.
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
31
0
8
0
0
8
0
47
16
8
0
0
% A
% Cys:
0
16
8
8
8
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
8
0
16
0
0
47
0
8
8
0
8
0
24
0
% D
% Glu:
16
0
16
0
8
16
8
8
0
8
0
31
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
8
0
16
8
8
0
0
8
8
0
0
0
8
0
8
% G
% His:
8
0
0
0
0
8
0
8
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
31
8
0
% I
% Lys:
39
0
0
0
0
0
0
16
0
16
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
8
8
0
0
8
8
0
8
% L
% Met:
0
0
0
8
0
0
16
0
8
0
0
0
0
0
0
% M
% Asn:
0
8
8
8
0
0
0
0
0
0
0
0
8
31
24
% N
% Pro:
0
0
39
8
8
0
0
0
31
24
0
8
8
8
0
% P
% Gln:
8
8
0
0
0
8
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
31
31
0
0
0
0
0
16
24
8
8
% R
% Ser:
8
47
0
0
8
0
8
24
16
0
8
16
0
16
39
% S
% Thr:
0
0
0
0
8
0
8
16
0
0
8
0
0
0
0
% T
% Val:
0
0
8
0
16
8
16
8
8
0
16
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
16
8
24
0
8
0
39
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _