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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEGF10 All Species: 9.7
Human Site: S1095 Identified Species: 17.78
UniProt: Q96KG7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96KG7 NP_115822.1 1140 122205 S1095 F S N N G R L S Q D P Y D L P
Chimpanzee Pan troglodytes XP_517907 1140 122173 S1095 F S N N G H L S Q D P Y D L P
Rhesus Macaque Macaca mulatta XP_001097941 1137 121871 F1088 V S V V Q G V F S N N G H L T
Dog Lupus familis XP_531893 1548 166681 F1499 V S V V Q G I F S N N G H L T
Cat Felis silvestris
Mouse Mus musculus Q6DIB5 1147 122953 T1095 F S N S G H V T Q D P Y D L P
Rat Rattus norvegicus O88281 1574 165428 L1522 R F G P G C A L R C D C G G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507076 1158 124996 G1108 F G N N V P F G Q D P Y D L P
Chicken Gallus gallus XP_424719 1278 138126 G1234 P T V S V V Q G A F N S S G R
Frog Xenopus laevis P21783 2524 275106 T2466 Y S S P M D N T P S H Q L Q V
Zebra Danio Brachydanio rerio P46530 2437 262289 L2100 M H H D I V R L L E E Y N L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728660 1031 112996 N987 E K P S N V K N M T V L L N K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XWD6 1111 118785 D1058 R P L L E E H D E E E F D E P
Sea Urchin Strong. purpuratus P10079 1064 112055 G1020 G Q C H L C D G E E V L Y T T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98.9 70.3 N.A. 94.3 27.5 N.A. 85.3 79.5 21.5 21.5 N.A. 35.2 N.A. 30.9 22.5
Protein Similarity: 100 99.6 99.4 72 N.A. 96.5 37 N.A. 91.2 83.9 29.6 30 N.A. 48.5 N.A. 46.9 36.6
P-Site Identity: 100 93.3 13.3 13.3 N.A. 73.3 6.6 N.A. 66.6 0 6.6 13.3 N.A. 0 N.A. 13.3 0
P-Site Similarity: 100 93.3 26.6 26.6 N.A. 93.3 13.3 N.A. 66.6 13.3 26.6 40 N.A. 13.3 N.A. 33.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % A
% Cys: 0 0 8 0 0 16 0 0 0 8 0 8 0 0 0 % C
% Asp: 0 0 0 8 0 8 8 8 0 31 8 0 39 0 0 % D
% Glu: 8 0 0 0 8 8 0 0 16 24 16 0 0 8 0 % E
% Phe: 31 8 0 0 0 0 8 16 0 8 0 8 0 0 0 % F
% Gly: 8 8 8 0 31 16 0 24 0 0 0 16 8 16 8 % G
% His: 0 8 8 8 0 16 8 0 0 0 8 0 16 0 0 % H
% Ile: 0 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 0 0 0 0 8 0 0 0 0 0 0 0 8 % K
% Leu: 0 0 8 8 8 0 16 16 8 0 0 16 16 54 0 % L
% Met: 8 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 31 24 8 0 8 8 0 16 24 0 8 8 0 % N
% Pro: 8 8 8 16 0 8 0 0 8 0 31 0 0 0 39 % P
% Gln: 0 8 0 0 16 0 8 0 31 0 0 8 0 8 0 % Q
% Arg: 16 0 0 0 0 8 8 0 8 0 0 0 0 0 8 % R
% Ser: 0 47 8 24 0 0 0 16 16 8 0 8 8 0 0 % S
% Thr: 0 8 0 0 0 0 0 16 0 8 0 0 0 8 24 % T
% Val: 16 0 24 16 16 24 16 0 0 0 16 0 0 0 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 39 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _