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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEGF10 All Species: 16.36
Human Site: S1122 Identified Species: 30
UniProt: Q96KG7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96KG7 NP_115822.1 1140 122205 S1122 P V R D S S S S P K Q E D S G
Chimpanzee Pan troglodytes XP_517907 1140 122173 S1122 P V R D S S S S P K Q E D S G
Rhesus Macaque Macaca mulatta XP_001097941 1137 121871 P1115 P C H Y D L L P V R D S S S S
Dog Lupus familis XP_531893 1548 166681 P1526 P C H Y D L L P V R D S S S S
Cat Felis silvestris
Mouse Mus musculus Q6DIB5 1147 122953 S1122 P V R D S S S S P K R E D G G
Rat Rattus norvegicus O88281 1574 165428 T1549 V D S Y M G P T C R E V P T Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507076 1158 124996 S1135 P V R D T P S S P K E E D C G
Chicken Gallus gallus XP_424719 1278 138126 L1261 H I P C H Y D L L P V R D S P
Frog Xenopus laevis P21783 2524 275106 S2493 P D Q W S S S S P H S N M S D
Zebra Danio Brachydanio rerio P46530 2437 262289 I2127 C P N T Y L G I K P S P G N N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728660 1031 112996 N1014 C F D N T N T N L D N V S T A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XWD6 1111 118785 P1085 T S N H N E N P Y A D I S S P
Sea Urchin Strong. purpuratus P10079 1064 112055 G1047 I K K S N M V G Q D K W T R Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98.9 70.3 N.A. 94.3 27.5 N.A. 85.3 79.5 21.5 21.5 N.A. 35.2 N.A. 30.9 22.5
Protein Similarity: 100 99.6 99.4 72 N.A. 96.5 37 N.A. 91.2 83.9 29.6 30 N.A. 48.5 N.A. 46.9 36.6
P-Site Identity: 100 100 13.3 13.3 N.A. 86.6 0 N.A. 73.3 13.3 46.6 0 N.A. 0 N.A. 6.6 0
P-Site Similarity: 100 100 20 20 N.A. 93.3 26.6 N.A. 86.6 20 53.3 6.6 N.A. 40 N.A. 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 8 % A
% Cys: 16 16 0 8 0 0 0 0 8 0 0 0 0 8 0 % C
% Asp: 0 16 8 31 16 0 8 0 0 16 24 0 39 0 8 % D
% Glu: 0 0 0 0 0 8 0 0 0 0 16 31 0 0 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 8 8 0 0 0 0 8 8 31 % G
% His: 8 0 16 8 8 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 8 8 0 0 0 0 0 8 0 0 0 8 0 0 0 % I
% Lys: 0 8 8 0 0 0 0 0 8 31 8 0 0 0 0 % K
% Leu: 0 0 0 0 0 24 16 8 16 0 0 0 0 0 0 % L
% Met: 0 0 0 0 8 8 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 16 8 16 8 8 8 0 0 8 8 0 8 8 % N
% Pro: 54 8 8 0 0 8 8 24 39 16 0 8 8 0 16 % P
% Gln: 0 0 8 0 0 0 0 0 8 0 16 0 0 0 8 % Q
% Arg: 0 0 31 0 0 0 0 0 0 24 8 8 0 8 0 % R
% Ser: 0 8 8 8 31 31 39 39 0 0 16 16 31 54 16 % S
% Thr: 8 0 0 8 16 0 8 8 0 0 0 0 8 16 0 % T
% Val: 8 31 0 0 0 0 8 0 16 0 8 16 0 0 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 0 24 8 8 0 0 8 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _