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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEGF10
All Species:
13.64
Human Site:
S1131
Identified Species:
25
UniProt:
Q96KG7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96KG7
NP_115822.1
1140
122205
S1131
K
Q
E
D
S
G
G
S
S
S
N
S
S
S
S
Chimpanzee
Pan troglodytes
XP_517907
1140
122173
S1131
K
Q
E
D
S
G
G
S
S
S
N
S
S
S
N
Rhesus Macaque
Macaca mulatta
XP_001097941
1137
121871
K1124
R
D
S
S
S
S
P
K
Q
E
D
S
G
G
S
Dog
Lupus familis
XP_531893
1548
166681
K1535
R
D
S
S
S
S
P
K
R
E
D
G
G
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6DIB5
1147
122953
S1131
K
R
E
D
G
G
G
S
N
S
T
S
S
N
S
Rat
Rattus norvegicus
O88281
1574
165428
S1558
R
E
V
P
T
Q
I
S
S
S
R
P
A
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507076
1158
124996
N1144
K
E
E
D
C
G
N
N
S
T
S
R
R
A
N
Chicken
Gallus gallus
XP_424719
1278
138126
S1270
P
V
R
D
S
P
T
S
S
T
K
E
V
G
S
Frog
Xenopus laevis
P21783
2524
275106
S2502
H
S
N
M
S
D
W
S
E
G
I
S
S
P
P
Zebra Danio
Brachydanio rerio
P46530
2437
262289
N2136
P
S
P
G
N
N
N
N
T
A
K
K
T
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728660
1031
112996
P1023
D
N
V
S
T
A
S
P
S
S
S
P
K
F
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XWD6
1111
118785
P1094
A
D
I
S
S
P
D
P
V
T
Q
N
S
A
N
Sea Urchin
Strong. purpuratus
P10079
1064
112055
Q1056
D
K
W
T
R
Y
E
Q
S
I
A
P
Q
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.9
70.3
N.A.
94.3
27.5
N.A.
85.3
79.5
21.5
21.5
N.A.
35.2
N.A.
30.9
22.5
Protein Similarity:
100
99.6
99.4
72
N.A.
96.5
37
N.A.
91.2
83.9
29.6
30
N.A.
48.5
N.A.
46.9
36.6
P-Site Identity:
100
93.3
20
13.3
N.A.
66.6
20
N.A.
33.3
33.3
26.6
0
N.A.
13.3
N.A.
13.3
6.6
P-Site Similarity:
100
100
33.3
26.6
N.A.
86.6
46.6
N.A.
73.3
40
26.6
33.3
N.A.
26.6
N.A.
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
0
0
8
8
0
8
16
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
24
0
39
0
8
8
0
0
0
16
0
0
0
8
% D
% Glu:
0
16
31
0
0
0
8
0
8
16
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
8
8
31
24
0
0
8
0
8
16
16
8
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
8
0
0
8
8
0
0
0
0
% I
% Lys:
31
8
0
0
0
0
0
16
0
0
16
8
8
0
8
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
8
8
16
16
8
0
16
8
0
8
24
% N
% Pro:
16
0
8
8
0
16
16
16
0
0
0
24
0
24
8
% P
% Gln:
0
16
0
0
0
8
0
8
8
0
8
0
8
0
8
% Q
% Arg:
24
8
8
0
8
0
0
0
8
0
8
8
8
8
0
% R
% Ser:
0
16
16
31
54
16
8
47
54
39
16
39
39
24
31
% S
% Thr:
0
0
0
8
16
0
8
0
8
24
8
0
8
0
0
% T
% Val:
0
8
16
0
0
0
0
0
8
0
0
0
8
0
0
% V
% Trp:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _