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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEGF10
All Species:
5.45
Human Site:
S1137
Identified Species:
10
UniProt:
Q96KG7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96KG7
NP_115822.1
1140
122205
S1137
G
S
S
S
N
S
S
S
S
S
E
_
_
_
_
Chimpanzee
Pan troglodytes
XP_517907
1140
122173
S1137
G
S
S
S
N
S
S
S
N
S
E
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001097941
1137
121871
G1130
P
K
Q
E
D
S
G
G
S
S
S
S
S
S
E
Dog
Lupus familis
XP_531893
1548
166681
S1541
P
K
R
E
D
G
G
S
G
S
S
S
S
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6DIB5
1147
122953
N1137
G
S
N
S
T
S
S
N
S
T
S
S
S
S
S
Rat
Rattus norvegicus
O88281
1574
165428
P1564
I
S
S
S
R
P
A
P
Q
H
P
S
S
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507076
1158
124996
A1150
N
N
S
T
S
R
R
A
N
L
E
I
P
F
S
Chicken
Gallus gallus
XP_424719
1278
138126
Frog
Xenopus laevis
P21783
2524
275106
P2508
W
S
E
G
I
S
S
P
P
T
S
M
Q
P
Q
Zebra Danio
Brachydanio rerio
P46530
2437
262289
R2142
N
N
T
A
K
K
T
R
K
P
G
G
K
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728660
1031
112996
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XWD6
1111
118785
A1100
D
P
V
T
Q
N
S
A
N
K
K
R
A
Q
D
Sea Urchin
Strong. purpuratus
P10079
1064
112055
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.9
70.3
N.A.
94.3
27.5
N.A.
85.3
79.5
21.5
21.5
N.A.
35.2
N.A.
30.9
22.5
Protein Similarity:
100
99.6
99.4
72
N.A.
96.5
37
N.A.
91.2
83.9
29.6
30
N.A.
48.5
N.A.
46.9
36.6
P-Site Identity:
100
90.9
20
13.3
N.A.
40
20
N.A.
13.3
0
20
0
N.A.
0
N.A.
6.6
0
P-Site Similarity:
100
100
26.6
20
N.A.
60
26.6
N.A.
53.3
0
26.6
40
N.A.
0
N.A.
40
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
16
0
0
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
16
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
8
16
0
0
0
0
0
0
24
0
0
0
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
24
0
0
8
0
8
16
8
8
0
8
8
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
16
0
0
8
8
0
0
8
8
8
0
8
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
16
16
8
0
16
8
0
8
24
0
0
0
0
0
0
% N
% Pro:
16
8
0
0
0
8
0
16
8
8
8
0
8
8
0
% P
% Gln:
0
0
8
0
8
0
0
0
8
0
0
0
8
8
8
% Q
% Arg:
0
0
8
0
8
8
8
8
0
0
0
8
0
8
0
% R
% Ser:
0
39
31
31
8
39
39
24
24
31
31
31
31
24
16
% S
% Thr:
0
0
8
16
8
0
8
0
0
16
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
16
16
16
16
% _