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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEGF10 All Species: 19.7
Human Site: S24 Identified Species: 36.11
UniProt: Q96KG7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96KG7 NP_115822.1 1140 122205 S24 C H W I G T A S P L N L E D P
Chimpanzee Pan troglodytes XP_517907 1140 122173 S24 C H W I G T A S P L N L E D P
Rhesus Macaque Macaca mulatta XP_001097941 1137 121871 S24 C Q W I G T A S P L N L E D P
Dog Lupus familis XP_531893 1548 166681 S435 C L W S R T A S A L N L E D P
Cat Felis silvestris
Mouse Mus musculus Q6DIB5 1147 122953 S24 C H W V G T A S S L N L E D P
Rat Rattus norvegicus O88281 1574 165428 P41 R P L Q P S M P H V C A E Q K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507076 1158 124996 S38 S H W I G L T S S L N L E D P
Chicken Gallus gallus XP_424719 1278 138126 L172 Y H W L G T T L S L N L E D P
Frog Xenopus laevis P21783 2524 275106 F58 Y F G E R C Q F P N P C T I K
Zebra Danio Brachydanio rerio P46530 2437 262289 H255 F T G Q T C E H N V D D C T Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728660 1031 112996
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XWD6 1111 118785 D25 T R A P T F P D K L T Q Q L Q
Sea Urchin Strong. purpuratus P10079 1064 112055 D24 T Y G Q G E C D S D P C E N G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98.9 70.3 N.A. 94.3 27.5 N.A. 85.3 79.5 21.5 21.5 N.A. 35.2 N.A. 30.9 22.5
Protein Similarity: 100 99.6 99.4 72 N.A. 96.5 37 N.A. 91.2 83.9 29.6 30 N.A. 48.5 N.A. 46.9 36.6
P-Site Identity: 100 100 93.3 73.3 N.A. 86.6 6.6 N.A. 73.3 66.6 6.6 0 N.A. 0 N.A. 6.6 13.3
P-Site Similarity: 100 100 93.3 73.3 N.A. 93.3 20 N.A. 73.3 73.3 6.6 13.3 N.A. 0 N.A. 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 39 0 8 0 0 8 0 0 0 % A
% Cys: 39 0 0 0 0 16 8 0 0 0 8 16 8 0 0 % C
% Asp: 0 0 0 0 0 0 0 16 0 8 8 8 0 54 0 % D
% Glu: 0 0 0 8 0 8 8 0 0 0 0 0 70 0 0 % E
% Phe: 8 8 0 0 0 8 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 24 0 54 0 0 0 0 0 0 0 0 0 8 % G
% His: 0 39 0 0 0 0 0 8 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 31 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 16 % K
% Leu: 0 8 8 8 0 8 0 8 0 62 0 54 0 8 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 8 54 0 0 8 0 % N
% Pro: 0 8 0 8 8 0 8 8 31 0 16 0 0 0 54 % P
% Gln: 0 8 0 24 0 0 8 0 0 0 0 8 8 8 16 % Q
% Arg: 8 8 0 0 16 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 0 0 8 0 8 0 47 31 0 0 0 0 0 0 % S
% Thr: 16 8 0 0 16 47 16 0 0 0 8 0 8 8 0 % T
% Val: 0 0 0 8 0 0 0 0 0 16 0 0 0 0 0 % V
% Trp: 0 0 54 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 16 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _