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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEGF10
All Species:
28.18
Human Site:
T949
Identified Species:
51.67
UniProt:
Q96KG7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96KG7
NP_115822.1
1140
122205
T949
V
N
N
R
D
R
M
T
V
T
K
S
K
N
N
Chimpanzee
Pan troglodytes
XP_517907
1140
122173
T949
V
N
N
R
D
R
M
T
V
T
K
S
K
N
N
Rhesus Macaque
Macaca mulatta
XP_001097941
1137
121871
T949
V
N
N
R
D
R
M
T
V
T
K
S
K
N
N
Dog
Lupus familis
XP_531893
1548
166681
T1360
V
N
N
R
D
R
M
T
I
A
K
S
K
N
N
Cat
Felis silvestris
Mouse
Mus musculus
Q6DIB5
1147
122953
T949
V
N
N
R
D
R
M
T
I
A
K
S
K
N
N
Rat
Rattus norvegicus
O88281
1574
165428
H1361
C
R
N
G
G
L
C
H
A
T
N
G
S
C
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507076
1158
124996
T963
V
N
L
R
D
R
M
T
I
A
K
T
D
K
S
Chicken
Gallus gallus
XP_424719
1278
138126
T1097
V
N
N
M
D
R
L
T
L
A
K
A
K
N
N
Frog
Xenopus laevis
P21783
2524
275106
S2222
M
T
S
P
F
Q
Q
S
P
S
M
P
L
N
H
Zebra Danio
Brachydanio rerio
P46530
2437
262289
S1929
L
A
A
R
Y
A
R
S
D
A
A
K
R
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728660
1031
112996
N850
N
P
P
S
W
P
P
N
H
N
F
D
N
P
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XWD6
1111
118785
I917
T
W
F
F
V
L
L
I
V
A
L
C
G
G
L
Sea Urchin
Strong. purpuratus
P10079
1064
112055
V883
V
N
V
G
A
D
Y
V
C
E
C
V
P
G
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.9
70.3
N.A.
94.3
27.5
N.A.
85.3
79.5
21.5
21.5
N.A.
35.2
N.A.
30.9
22.5
Protein Similarity:
100
99.6
99.4
72
N.A.
96.5
37
N.A.
91.2
83.9
29.6
30
N.A.
48.5
N.A.
46.9
36.6
P-Site Identity:
100
100
100
86.6
N.A.
86.6
13.3
N.A.
53.3
66.6
6.6
6.6
N.A.
0
N.A.
6.6
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
20
N.A.
73.3
86.6
46.6
26.6
N.A.
0
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
8
8
0
0
8
47
8
8
0
0
0
% A
% Cys:
8
0
0
0
0
0
8
0
8
0
8
8
0
8
0
% C
% Asp:
0
0
0
0
54
8
0
0
8
0
0
8
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
8
8
8
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
16
8
0
0
0
0
0
0
8
8
16
0
% G
% His:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
8
24
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
54
8
47
8
0
% K
% Leu:
8
0
8
0
0
16
16
0
8
0
8
0
8
8
16
% L
% Met:
8
0
0
8
0
0
47
0
0
0
8
0
0
0
0
% M
% Asn:
8
62
54
0
0
0
0
8
0
8
8
0
8
54
47
% N
% Pro:
0
8
8
8
0
8
8
0
8
0
0
8
8
8
0
% P
% Gln:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
54
0
54
8
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
8
8
0
0
0
16
0
8
0
39
8
0
16
% S
% Thr:
8
8
0
0
0
0
0
54
0
31
0
8
0
0
0
% T
% Val:
62
0
8
0
8
0
0
8
31
0
0
8
0
0
8
% V
% Trp:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _