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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCYL1
All Species:
13.64
Human Site:
S269
Identified Species:
25
UniProt:
Q96KG9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96KG9
NP_001041683.1
808
89631
S269
R
A
P
G
G
F
M
S
N
R
F
V
E
T
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113724
803
88486
S269
R
A
P
G
G
F
M
S
N
R
F
V
E
T
N
Dog
Lupus familis
XP_540858
735
81171
A263
R
F
L
Q
N
C
R
A
P
G
G
F
M
N
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQC5
806
89141
S269
R
A
P
G
G
F
M
S
N
R
F
V
E
T
N
Rat
Rattus norvegicus
Q5M9F8
807
89107
S269
R
A
P
G
G
F
M
S
N
R
F
V
E
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q561M0
827
91284
C264
R
S
P
G
G
F
F
C
N
S
F
V
E
T
N
Zebra Danio
Brachydanio rerio
XP_001332508
855
94229
N266
R
S
P
G
G
F
M
N
N
S
F
V
E
S
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651722
873
97142
K269
R
K
P
G
G
F
F
K
N
D
L
V
D
T
L
Honey Bee
Apis mellifera
XP_395225
783
87985
K269
R
S
N
G
G
F
F
K
N
E
L
V
D
A
L
Nematode Worm
Caenorhab. elegans
NP_506259
820
90147
K231
R
L
T
G
G
Y
L
K
N
K
F
V
D
T
L
Sea Urchin
Strong. purpuratus
XP_001203708
977
106946
K266
Q
N
S
G
G
F
M
K
N
S
F
V
D
T
N
Poplar Tree
Populus trichocarpa
XP_002319344
800
86267
Q287
L
E
N
S
E
Y
F
Q
N
K
L
V
D
T
I
Maize
Zea mays
NP_001146277
823
89416
Q285
I
D
N
S
E
F
F
Q
N
K
L
V
E
T
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.3
83.6
N.A.
90.9
90.8
N.A.
N.A.
N.A.
65.1
64.8
N.A.
45.9
41.9
36.3
46.2
Protein Similarity:
100
N.A.
95.3
86.5
N.A.
93.5
93.9
N.A.
N.A.
N.A.
76.9
74.8
N.A.
61.1
57.9
54.2
59.4
P-Site Identity:
100
N.A.
100
13.3
N.A.
100
100
N.A.
N.A.
N.A.
73.3
66.6
N.A.
53.3
40
46.6
60
P-Site Similarity:
100
N.A.
100
20
N.A.
100
100
N.A.
N.A.
N.A.
80
86.6
N.A.
60
53.3
73.3
73.3
Percent
Protein Identity:
32
32.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
51.1
50.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
33.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
40
40
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
31
0
0
0
0
0
8
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
8
% C
% Asp:
0
8
0
0
0
0
0
0
0
8
0
0
39
0
0
% D
% Glu:
0
8
0
0
16
0
0
0
0
8
0
0
54
0
0
% E
% Phe:
0
8
0
0
0
77
39
0
0
0
62
8
0
0
0
% F
% Gly:
0
0
0
77
77
0
0
0
0
8
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% I
% Lys:
0
8
0
0
0
0
0
31
0
24
0
0
0
0
0
% K
% Leu:
8
8
8
0
0
0
8
0
0
0
31
0
0
0
24
% L
% Met:
0
0
0
0
0
0
47
0
0
0
0
0
8
0
0
% M
% Asn:
0
8
24
0
8
0
0
8
93
0
0
0
0
8
54
% N
% Pro:
0
0
54
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
8
0
0
8
0
0
0
16
0
0
0
0
0
0
0
% Q
% Arg:
77
0
0
0
0
0
8
0
0
31
0
0
0
0
0
% R
% Ser:
0
24
8
16
0
0
0
31
0
24
0
0
0
8
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
0
0
0
77
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
93
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _