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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCYL1
All Species:
21.82
Human Site:
S535
Identified Species:
40
UniProt:
Q96KG9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96KG9
NP_001041683.1
808
89631
S535
K
A
I
R
S
F
L
S
K
L
E
S
V
S
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113724
803
88486
S530
K
A
I
R
S
F
L
S
K
L
E
S
V
S
E
Dog
Lupus familis
XP_540858
735
81171
T494
G
V
L
G
F
A
A
T
H
N
L
Y
S
M
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQC5
806
89141
S535
K
T
I
R
S
F
L
S
K
L
E
S
V
S
E
Rat
Rattus norvegicus
Q5M9F8
807
89107
S535
K
T
I
R
S
F
L
S
K
L
E
S
V
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q561M0
827
91284
D530
K
T
I
R
S
F
L
D
K
L
E
T
V
S
G
Zebra Danio
Brachydanio rerio
XP_001332508
855
94229
S532
K
A
I
K
S
F
L
S
K
L
E
T
V
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651722
873
97142
G535
K
T
I
R
G
F
L
G
K
L
E
K
V
S
E
Honey Bee
Apis mellifera
XP_395225
783
87985
S535
R
T
I
R
G
F
L
S
K
L
E
R
V
S
E
Nematode Worm
Caenorhab. elegans
NP_506259
820
90147
E497
K
A
I
R
G
F
L
E
K
L
E
K
A
S
E
Sea Urchin
Strong. purpuratus
XP_001203708
977
106946
G532
K
A
I
K
I
F
L
G
K
L
E
K
V
S
Q
Poplar Tree
Populus trichocarpa
XP_002319344
800
86267
Q553
Q
A
A
E
Q
F
L
Q
I
V
K
Q
Y
H
E
Maize
Zea mays
NP_001146277
823
89416
Q551
Q
A
T
D
Q
F
L
Q
I
A
K
Q
H
H
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.3
83.6
N.A.
90.9
90.8
N.A.
N.A.
N.A.
65.1
64.8
N.A.
45.9
41.9
36.3
46.2
Protein Similarity:
100
N.A.
95.3
86.5
N.A.
93.5
93.9
N.A.
N.A.
N.A.
76.9
74.8
N.A.
61.1
57.9
54.2
59.4
P-Site Identity:
100
N.A.
100
0
N.A.
93.3
93.3
N.A.
N.A.
N.A.
73.3
86.6
N.A.
73.3
73.3
73.3
66.6
P-Site Similarity:
100
N.A.
100
13.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
80
100
N.A.
73.3
80
73.3
80
Percent
Protein Identity:
32
32.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
51.1
50.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
26.6
26.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
46.6
40
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
54
8
0
0
8
8
0
0
8
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
8
0
0
77
0
0
0
77
% E
% Phe:
0
0
0
0
8
93
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
8
24
0
0
16
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
8
16
0
% H
% Ile:
0
0
77
0
8
0
0
0
16
0
0
0
0
0
0
% I
% Lys:
70
0
0
16
0
0
0
0
77
0
16
24
0
0
0
% K
% Leu:
0
0
8
0
0
0
93
0
0
77
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
16
0
0
0
16
0
0
16
0
0
0
16
0
0
8
% Q
% Arg:
8
0
0
62
0
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
0
0
0
0
47
0
0
47
0
0
0
31
8
77
0
% S
% Thr:
0
39
8
0
0
0
0
8
0
0
0
16
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
0
8
0
0
70
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _