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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCYL1
All Species:
13.64
Human Site:
S679
Identified Species:
25
UniProt:
Q96KG9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96KG9
NP_001041683.1
808
89631
S679
V
S
R
A
S
Q
V
S
N
S
D
H
K
S
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113724
803
88486
S674
V
S
H
A
S
Q
V
S
N
S
D
H
K
P
S
Dog
Lupus familis
XP_540858
735
81171
S638
S
T
D
T
A
E
D
S
S
A
A
D
R
W
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQC5
806
89141
H679
S
R
A
G
Q
I
N
H
P
D
H
K
S
L
E
Rat
Rattus norvegicus
Q5M9F8
807
89107
S679
G
N
R
A
G
Q
V
S
H
S
D
H
K
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q561M0
827
91284
K674
G
Q
S
K
T
Q
Q
K
T
V
H
S
S
S
S
Zebra Danio
Brachydanio rerio
XP_001332508
855
94229
S676
V
S
S
T
Q
K
K
S
N
V
G
R
K
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651722
873
97142
S679
L
M
A
A
N
A
L
S
E
V
R
D
G
W
D
Honey Bee
Apis mellifera
XP_395225
783
87985
P679
H
G
S
N
N
I
S
P
S
S
H
S
P
K
P
Nematode Worm
Caenorhab. elegans
NP_506259
820
90147
A641
V
G
W
D
T
P
I
A
T
A
T
S
S
P
I
Sea Urchin
Strong. purpuratus
XP_001203708
977
106946
G676
E
W
D
S
Q
G
W
G
D
D
Y
D
D
D
M
Poplar Tree
Populus trichocarpa
XP_002319344
800
86267
P697
I
Q
A
A
Q
K
R
P
V
S
Q
P
V
S
Q
Maize
Zea mays
NP_001146277
823
89416
R695
N
I
Q
A
A
Q
K
R
P
V
V
Q
P
K
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.3
83.6
N.A.
90.9
90.8
N.A.
N.A.
N.A.
65.1
64.8
N.A.
45.9
41.9
36.3
46.2
Protein Similarity:
100
N.A.
95.3
86.5
N.A.
93.5
93.9
N.A.
N.A.
N.A.
76.9
74.8
N.A.
61.1
57.9
54.2
59.4
P-Site Identity:
100
N.A.
86.6
6.6
N.A.
0
66.6
N.A.
N.A.
N.A.
20
46.6
N.A.
13.3
6.6
6.6
0
P-Site Similarity:
100
N.A.
86.6
46.6
N.A.
0
80
N.A.
N.A.
N.A.
26.6
53.3
N.A.
33.3
20
33.3
13.3
Percent
Protein Identity:
32
32.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
51.1
50.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
24
47
16
8
0
8
0
16
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
16
8
0
0
8
0
8
16
24
24
8
8
16
% D
% Glu:
8
0
0
0
0
8
0
0
8
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
16
0
8
8
8
0
8
0
0
8
0
8
0
0
% G
% His:
8
0
8
0
0
0
0
8
8
0
24
24
0
0
0
% H
% Ile:
8
8
0
0
0
16
8
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
8
0
16
16
8
0
0
0
8
31
16
0
% K
% Leu:
8
0
0
0
0
0
8
0
0
0
0
0
0
8
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
8
0
8
16
0
8
0
24
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
16
16
0
0
8
16
16
8
% P
% Gln:
0
16
8
0
31
39
8
0
0
0
8
8
0
0
16
% Q
% Arg:
0
8
16
0
0
0
8
8
0
0
8
8
8
0
0
% R
% Ser:
16
24
24
8
16
0
8
47
16
39
0
24
24
39
31
% S
% Thr:
0
8
0
16
16
0
0
0
16
0
8
0
0
0
0
% T
% Val:
31
0
0
0
0
0
24
0
8
31
8
0
8
0
0
% V
% Trp:
0
8
8
0
0
0
8
0
0
0
0
0
0
16
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _