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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCYL1
All Species:
4.55
Human Site:
S754
Identified Species:
8.33
UniProt:
Q96KG9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96KG9
NP_001041683.1
808
89631
S754
S
T
Q
P
R
P
D
S
W
G
E
D
N
W
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113724
803
88486
S749
S
T
Q
P
R
P
D
S
W
G
E
D
N
W
E
Dog
Lupus familis
XP_540858
735
81171
M713
R
E
E
R
R
R
E
M
E
A
K
R
A
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQC5
806
89141
G754
R
P
D
P
D
S
W
G
E
D
N
W
E
G
L
Rat
Rattus norvegicus
Q5M9F8
807
89107
W754
P
R
P
D
P
D
S
W
G
E
D
N
W
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q561M0
827
91284
F749
T
A
G
Q
Q
G
D
F
F
T
T
L
S
E
H
Zebra Danio
Brachydanio rerio
XP_001332508
855
94229
A751
S
S
A
A
T
K
S
A
S
S
A
Q
D
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651722
873
97142
E754
H
E
L
N
D
L
I
E
P
L
A
K
L
N
S
Honey Bee
Apis mellifera
XP_395225
783
87985
K754
K
L
K
E
A
R
R
K
R
E
E
G
K
L
A
Nematode Worm
Caenorhab. elegans
NP_506259
820
90147
A716
V
K
P
N
S
L
N
A
L
M
N
N
S
S
S
Sea Urchin
Strong. purpuratus
XP_001203708
977
106946
K751
K
P
I
K
T
S
S
K
L
S
K
S
Q
S
G
Poplar Tree
Populus trichocarpa
XP_002319344
800
86267
P772
P
P
T
T
R
A
K
P
L
V
A
G
R
G
R
Maize
Zea mays
NP_001146277
823
89416
P770
S
S
G
K
P
L
K
P
A
V
A
N
S
D
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.3
83.6
N.A.
90.9
90.8
N.A.
N.A.
N.A.
65.1
64.8
N.A.
45.9
41.9
36.3
46.2
Protein Similarity:
100
N.A.
95.3
86.5
N.A.
93.5
93.9
N.A.
N.A.
N.A.
76.9
74.8
N.A.
61.1
57.9
54.2
59.4
P-Site Identity:
100
N.A.
100
6.6
N.A.
6.6
0
N.A.
N.A.
N.A.
6.6
6.6
N.A.
0
6.6
0
0
P-Site Similarity:
100
N.A.
100
33.3
N.A.
6.6
13.3
N.A.
N.A.
N.A.
33.3
26.6
N.A.
0
13.3
26.6
6.6
Percent
Protein Identity:
32
32.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
51.1
50.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
8
8
0
16
8
8
31
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
16
8
24
0
0
8
8
16
8
8
8
% D
% Glu:
0
16
8
8
0
0
8
8
16
16
24
0
8
24
16
% E
% Phe:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% F
% Gly:
0
0
16
0
0
8
0
8
8
16
0
16
0
24
16
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
16
8
8
16
0
8
16
16
0
0
16
8
8
0
8
% K
% Leu:
0
8
8
0
0
24
0
0
24
8
0
8
8
8
8
% L
% Met:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
16
0
0
8
0
0
0
16
24
16
8
0
% N
% Pro:
16
24
16
24
16
16
0
16
8
0
0
0
0
0
0
% P
% Gln:
0
0
16
8
8
0
0
0
0
0
0
8
8
0
0
% Q
% Arg:
16
8
0
8
31
16
8
0
8
0
0
8
8
0
8
% R
% Ser:
31
16
0
0
8
16
24
16
8
16
0
8
24
16
16
% S
% Thr:
8
16
8
8
16
0
0
0
0
8
8
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
16
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
8
8
16
0
0
8
8
16
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _