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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCYL1
All Species:
33.03
Human Site:
Y184
Identified Species:
60.56
UniProt:
Q96KG9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96KG9
NP_001041683.1
808
89631
Y184
G
I
P
E
L
E
Q
Y
D
P
P
E
L
A
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113724
803
88486
Y184
G
I
P
E
L
E
Q
Y
D
P
P
E
L
A
D
Dog
Lupus familis
XP_540858
735
81171
Y184
G
V
P
E
L
E
Q
Y
D
P
P
E
L
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQC5
806
89141
Y184
G
I
P
E
L
E
Q
Y
D
P
P
E
L
A
D
Rat
Rattus norvegicus
Q5M9F8
807
89107
Y184
G
I
P
E
L
E
Q
Y
D
P
P
E
L
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q561M0
827
91284
K179
R
K
G
V
E
M
E
K
Y
N
P
P
E
K
T
Zebra Danio
Brachydanio rerio
XP_001332508
855
94229
Y185
I
N
P
D
L
E
R
Y
D
P
P
E
S
P
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651722
873
97142
Y184
I
P
V
T
L
E
V
Y
D
S
P
E
K
N
D
Honey Bee
Apis mellifera
XP_395225
783
87985
Y186
L
P
S
T
F
Q
A
Y
Y
P
P
D
V
K
E
Nematode Worm
Caenorhab. elegans
NP_506259
820
90147
V174
D
L
N
Q
L
A
I
V
L
W
E
V
F
N
G
Sea Urchin
Strong. purpuratus
XP_001203708
977
106946
Y181
G
L
R
S
L
E
K
Y
N
P
P
E
M
T
D
Poplar Tree
Populus trichocarpa
XP_002319344
800
86267
Y203
E
W
L
I
G
S
Q
Y
K
P
M
E
L
A
K
Maize
Zea mays
NP_001146277
823
89416
Y201
E
W
L
V
G
T
Q
Y
K
P
M
E
L
S
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.3
83.6
N.A.
90.9
90.8
N.A.
N.A.
N.A.
65.1
64.8
N.A.
45.9
41.9
36.3
46.2
Protein Similarity:
100
N.A.
95.3
86.5
N.A.
93.5
93.9
N.A.
N.A.
N.A.
76.9
74.8
N.A.
61.1
57.9
54.2
59.4
P-Site Identity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
N.A.
N.A.
6.6
53.3
N.A.
46.6
20
6.6
53.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
N.A.
13.3
73.3
N.A.
46.6
46.6
20
80
Percent
Protein Identity:
32
32.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
51.1
50.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
40
33.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
40
40
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
8
0
0
0
0
0
0
47
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
0
0
54
0
0
8
0
0
54
% D
% Glu:
16
0
0
39
8
62
8
0
0
0
8
77
8
0
8
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
47
0
8
0
16
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
16
31
0
8
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
8
8
16
0
0
0
8
16
16
% K
% Leu:
8
16
16
0
70
0
0
0
8
0
0
0
54
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
16
0
8
0
0
% M
% Asn:
0
8
8
0
0
0
0
0
8
8
0
0
0
16
8
% N
% Pro:
0
16
47
0
0
0
0
0
0
77
77
8
0
8
0
% P
% Gln:
0
0
0
8
0
8
54
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
8
0
8
0
0
0
8
0
0
8
8
0
% S
% Thr:
0
0
0
16
0
8
0
0
0
0
0
0
0
8
8
% T
% Val:
0
8
8
16
0
0
8
8
0
0
0
8
8
0
0
% V
% Trp:
0
16
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
85
16
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _