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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCYL1
All Species:
23.33
Human Site:
Y458
Identified Species:
42.78
UniProt:
Q96KG9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96KG9
NP_001041683.1
808
89631
Y458
C
L
G
K
I
G
S
Y
L
S
A
S
T
R
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113724
803
88486
Y453
C
L
G
K
I
G
S
Y
L
S
A
S
T
R
H
Dog
Lupus familis
XP_540858
735
81171
K418
S
M
L
L
L
A
P
K
L
N
E
A
N
L
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQC5
806
89141
Y458
C
L
G
K
I
G
S
Y
L
S
A
S
T
R
H
Rat
Rattus norvegicus
Q5M9F8
807
89107
Y458
C
L
G
K
I
G
S
Y
L
S
A
S
T
R
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q561M0
827
91284
Y453
C
L
G
K
I
A
P
Y
L
N
P
A
T
R
Q
Zebra Danio
Brachydanio rerio
XP_001332508
855
94229
Y455
C
L
G
K
I
A
P
Y
L
N
A
G
M
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651722
873
97142
H458
C
L
G
K
I
A
P
H
L
H
P
Q
V
R
Q
Honey Bee
Apis mellifera
XP_395225
783
87985
H458
C
L
G
K
I
A
Q
H
L
H
P
Q
I
R
Q
Nematode Worm
Caenorhab. elegans
NP_506259
820
90147
L420
C
L
G
K
I
G
H
L
I
A
P
A
K
R
Q
Sea Urchin
Strong. purpuratus
XP_001203708
977
106946
Y455
C
L
G
K
L
A
G
Y
L
N
P
T
T
R
Q
Poplar Tree
Populus trichocarpa
XP_002319344
800
86267
L476
L
G
N
I
A
S
Y
L
N
E
G
T
R
K
R
Maize
Zea mays
NP_001146277
823
89416
M474
L
G
N
I
A
G
Y
M
N
D
G
T
R
K
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.3
83.6
N.A.
90.9
90.8
N.A.
N.A.
N.A.
65.1
64.8
N.A.
45.9
41.9
36.3
46.2
Protein Similarity:
100
N.A.
95.3
86.5
N.A.
93.5
93.9
N.A.
N.A.
N.A.
76.9
74.8
N.A.
61.1
57.9
54.2
59.4
P-Site Identity:
100
N.A.
100
6.6
N.A.
100
100
N.A.
N.A.
N.A.
60
60
N.A.
46.6
46.6
46.6
53.3
P-Site Similarity:
100
N.A.
100
40
N.A.
100
100
N.A.
N.A.
N.A.
73.3
66.6
N.A.
53.3
53.3
66.6
73.3
Percent
Protein Identity:
32
32.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
51.1
50.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
16
47
0
0
0
8
39
24
0
0
0
% A
% Cys:
77
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
16
77
0
0
47
8
0
0
0
16
8
0
0
0
% G
% His:
0
0
0
0
0
0
8
16
0
16
0
0
0
0
31
% H
% Ile:
0
0
0
16
70
0
0
0
8
0
0
0
8
0
0
% I
% Lys:
0
0
0
77
0
0
0
8
0
0
0
0
8
16
0
% K
% Leu:
16
77
8
8
16
0
0
16
77
0
0
0
0
8
0
% L
% Met:
0
8
0
0
0
0
0
8
0
0
0
0
8
0
0
% M
% Asn:
0
0
16
0
0
0
0
0
16
31
0
0
8
0
8
% N
% Pro:
0
0
0
0
0
0
31
0
0
0
39
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
16
0
0
47
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
16
77
16
% R
% Ser:
8
0
0
0
0
8
31
0
0
31
0
31
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
24
47
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
16
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _