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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COX4I2
All Species:
4.24
Human Site:
S24
Identified Species:
9.33
UniProt:
Q96KJ9
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96KJ9
NP_115998.2
171
20010
S24
G
R
R
G
M
H
S
S
E
G
T
T
R
G
G
Chimpanzee
Pan troglodytes
O46577
144
16844
D15
F
S
L
P
A
Y
M
D
R
R
D
H
P
L
P
Rhesus Macaque
Macaca mulatta
XP_001110371
171
20186
S24
G
R
R
G
M
H
S
S
E
G
T
A
R
G
G
Dog
Lupus familis
XP_542949
151
17909
A22
P
P
Y
T
N
Y
H
A
Q
R
S
Y
P
M
P
Cat
Felis silvestris
Mouse
Mus musculus
Q91W29
172
20188
P25
R
G
T
G
T
H
S
P
G
D
A
A
G
S
Q
Rat
Rattus norvegicus
Q91Y94
172
20152
G25
T
Q
G
T
H
S
P
G
S
A
A
S
S
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507221
169
19525
H24
T
S
V
C
V
R
G
H
A
G
V
V
K
T
E
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079903
174
20525
H27
A
A
S
I
R
A
A
H
S
H
E
G
Q
V
S
Zebra Danio
Brachydanio rerio
NP_957097
177
20186
H31
S
S
V
K
M
A
S
H
G
H
G
D
V
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610013
182
20501
L33
S
V
A
A
V
H
T
L
D
K
I
G
K
R
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796538
162
18668
D26
T
P
K
R
N
F
H
D
K
L
Y
A
D
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.1
91.8
74.8
N.A.
73.8
70.9
N.A.
42.1
N.A.
52.2
45.7
N.A.
36.8
N.A.
N.A.
41.5
Protein Similarity:
100
62.5
94.7
80.6
N.A.
83.1
82.5
N.A.
65.5
N.A.
70.1
63.8
N.A.
50
N.A.
N.A.
59.6
P-Site Identity:
100
0
93.3
0
N.A.
20
0
N.A.
6.6
N.A.
0
13.3
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
6.6
93.3
26.6
N.A.
20
13.3
N.A.
20
N.A.
13.3
13.3
N.A.
33.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
10
10
19
10
10
10
10
19
28
0
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
19
10
10
10
10
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
19
0
10
0
0
0
28
% E
% Phe:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
10
10
28
0
0
10
10
19
28
10
19
10
19
19
% G
% His:
0
0
0
0
10
37
19
28
0
19
0
10
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
10
0
0
10
0
% I
% Lys:
0
0
10
10
0
0
0
0
10
10
0
0
19
0
0
% K
% Leu:
0
0
10
0
0
0
0
10
0
10
0
0
0
10
10
% L
% Met:
0
0
0
0
28
0
10
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
19
0
10
0
0
10
10
0
0
0
0
19
0
19
% P
% Gln:
0
10
0
0
0
0
0
0
10
0
0
0
10
0
19
% Q
% Arg:
10
19
19
10
10
10
0
0
10
19
0
0
19
19
0
% R
% Ser:
19
28
10
0
0
10
37
19
19
0
10
10
10
19
10
% S
% Thr:
28
0
10
19
10
0
10
0
0
0
19
10
0
10
0
% T
% Val:
0
10
19
0
19
0
0
0
0
0
10
10
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
19
0
0
0
0
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _