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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNS1
All Species:
22.73
Human Site:
S488
Identified Species:
55.56
UniProt:
Q96KK3
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96KK3
NP_002242.2
526
58372
S488
E
F
E
D
L
L
S
S
I
D
G
V
S
E
A
Chimpanzee
Pan troglodytes
A4K2N8
526
58395
S488
E
F
E
D
L
L
S
S
V
D
G
V
S
E
A
Rhesus Macaque
Macaca mulatta
A4K2T1
529
58315
S491
E
F
E
D
L
L
S
S
V
D
G
V
S
E
A
Dog
Lupus familis
XP_543013
498
54671
S460
E
F
E
D
L
L
S
S
V
D
G
V
S
E
V
Cat
Felis silvestris
Mouse
Mus musculus
O35173
497
54885
S459
E
F
E
D
L
L
S
S
V
D
G
V
S
D
V
Rat
Rattus norvegicus
O88758
497
54896
S459
E
F
E
D
L
L
S
S
V
D
G
V
S
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506624
494
56597
I455
A
R
R
M
H
S
F
I
S
S
L
S
S
V
G
Chicken
Gallus gallus
O73606
518
58750
R473
Q
Q
Q
R
A
A
S
R
Q
M
H
Q
L
E
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922193
487
55898
H450
G
D
S
A
I
H
G
H
I
H
C
L
E
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17970
985
106341
S690
D
R
A
K
R
E
G
S
I
V
S
F
H
H
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.5
86.6
N.A.
84.9
85.7
N.A.
44.4
31.5
N.A.
54.1
N.A.
21.4
N.A.
N.A.
N.A.
Protein Similarity:
100
100
97.5
89.3
N.A.
87.6
88.5
N.A.
62.7
51.9
N.A.
69.5
N.A.
31.3
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
86.6
N.A.
80
80
N.A.
6.6
13.3
N.A.
6.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
6.6
26.6
N.A.
26.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
10
10
0
0
0
0
0
0
0
0
30
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
10
10
0
60
0
0
0
0
0
60
0
0
0
30
0
% D
% Glu:
60
0
60
0
0
10
0
0
0
0
0
0
10
50
20
% E
% Phe:
0
60
0
0
0
0
10
0
0
0
0
10
0
0
0
% F
% Gly:
10
0
0
0
0
0
20
0
0
0
60
0
0
0
10
% G
% His:
0
0
0
0
10
10
0
10
0
10
10
0
10
10
0
% H
% Ile:
0
0
0
0
10
0
0
10
30
0
0
0
0
0
10
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
60
60
0
0
0
0
10
10
10
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
10
10
0
0
0
0
0
10
0
0
10
0
0
0
% Q
% Arg:
0
20
10
10
10
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
10
70
70
10
10
10
10
70
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
50
10
0
60
0
10
30
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _