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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRASLS5
All Species:
12.73
Human Site:
S169
Identified Species:
40
UniProt:
Q96KN8
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.43
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96KN8
NP_473449.1
279
30312
S169
S
E
E
F
E
V
G
S
I
T
S
I
F
S
N
Chimpanzee
Pan troglodytes
XP_508512
279
30323
S169
S
E
E
F
E
V
G
S
I
T
S
I
F
S
N
Rhesus Macaque
Macaca mulatta
XP_001115819
279
30434
S169
S
E
E
F
E
V
G
S
I
S
S
I
F
S
N
Dog
Lupus familis
XP_533254
227
25047
F122
A
G
S
I
T
S
V
F
S
N
R
A
V
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CPX5
270
29847
S160
P
S
E
F
E
A
G
S
I
T
S
I
F
S
N
Rat
Rattus norvegicus
P53817
160
17730
K55
I
M
S
A
L
T
D
K
A
I
V
K
K
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513952
195
21984
K90
I
M
S
A
L
T
D
K
A
L
V
K
K
E
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002590
169
18568
R63
S
V
K
S
V
F
S
R
K
A
V
V
R
M
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
94.2
66.3
N.A.
71.3
25.4
N.A.
33.3
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
95.3
72.4
N.A.
76.3
36.5
N.A.
42.6
N.A.
N.A.
34.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
0
N.A.
80
0
N.A.
0
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
80
0
N.A.
0
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
25
0
13
0
0
25
13
0
13
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
25
0
0
0
0
0
0
0
0
% D
% Glu:
0
38
50
0
50
0
0
0
0
0
0
0
0
25
0
% E
% Phe:
0
0
0
50
0
13
0
13
0
0
0
0
50
0
0
% F
% Gly:
0
13
0
0
0
0
50
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
25
0
0
13
0
0
0
0
50
13
0
50
0
0
0
% I
% Lys:
0
0
13
0
0
0
0
25
13
0
0
25
25
0
13
% K
% Leu:
0
0
0
0
25
0
0
0
0
13
0
0
0
0
25
% L
% Met:
0
25
0
0
0
0
0
0
0
0
0
0
0
13
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
50
% N
% Pro:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% Q
% Arg:
0
0
0
0
0
0
0
13
0
0
13
0
13
0
0
% R
% Ser:
50
13
38
13
0
13
13
50
13
13
50
0
0
50
0
% S
% Thr:
0
0
0
0
13
25
0
0
0
38
0
0
0
0
0
% T
% Val:
0
13
0
0
13
38
13
0
0
0
38
13
13
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _