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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZFR All Species: 23.94
Human Site: S445 Identified Species: 47.88
UniProt: Q96KR1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96KR1 NP_057191.2 1074 117012 S445 S A S K P T A S P S S I A A N
Chimpanzee Pan troglodytes XP_001155370 1030 112531 T426 T S S M K G L T T T G N S S L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_546357 1073 116879 S445 S A S K P T A S P S S I A A S
Cat Felis silvestris
Mouse Mus musculus O88532 1074 116840 S445 S A S K P T A S P S S I G A S
Rat Rattus norvegicus Q562A2 1073 116800 S443 S A S K P T A S P S S I G A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508407 1102 120156 A473 A S A S K P T A S T S S I S S
Chicken Gallus gallus XP_424997 1045 113993 S425 S A S S I A T S S S T V N S S
Frog Xenopus laevis Q6GPM1 1054 115199 S436 K A S A T S S S T S S A N G S
Zebra Danio Brachydanio rerio Q6PCR6 1074 116505 S439 T A A P N K T S S S N I N S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_788510 884 96010 C371 L S F N C K L C D C K F N D P
Honey Bee Apis mellifera XP_624428 928 100974 Q415 K D I Q P V G Q E Y I E E N K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001182008 936 104584 S423 N E E G K L V S F N C K L C E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.8 N.A. 98.9 N.A. 97.7 94.4 N.A. 89.2 90.5 84.8 80.2 N.A. 39.1 47.2 N.A. 43.2
Protein Similarity: 100 95.9 N.A. 99.6 N.A. 99 96.4 N.A. 93 94 91.9 88.6 N.A. 52.3 58.8 N.A. 56.4
P-Site Identity: 100 6.6 N.A. 93.3 N.A. 86.6 86.6 N.A. 6.6 33.3 33.3 26.6 N.A. 0 6.6 N.A. 6.6
P-Site Similarity: 100 46.6 N.A. 100 N.A. 93.3 93.3 N.A. 53.3 60 53.3 60 N.A. 6.6 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 59 17 9 0 9 34 9 0 0 0 9 17 34 0 % A
% Cys: 0 0 0 0 9 0 0 9 0 9 9 0 0 9 0 % C
% Asp: 0 9 0 0 0 0 0 0 9 0 0 0 0 9 0 % D
% Glu: 0 9 9 0 0 0 0 0 9 0 0 9 9 0 9 % E
% Phe: 0 0 9 0 0 0 0 0 9 0 0 9 0 0 0 % F
% Gly: 0 0 0 9 0 9 9 0 0 0 9 0 17 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 0 9 0 0 0 0 0 9 42 9 0 0 % I
% Lys: 17 0 0 34 25 17 0 0 0 0 9 9 0 0 9 % K
% Leu: 9 0 0 0 0 9 17 0 0 0 0 0 9 0 9 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 9 9 0 0 0 0 9 9 9 34 9 9 % N
% Pro: 0 0 0 9 42 9 0 0 34 0 0 0 0 0 9 % P
% Gln: 0 0 0 9 0 0 0 9 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 42 25 59 17 0 9 9 67 25 59 50 9 9 34 59 % S
% Thr: 17 0 0 0 9 34 25 9 17 17 9 0 0 0 0 % T
% Val: 0 0 0 0 0 9 9 0 0 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _