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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZFR All Species: 3.94
Human Site: S546 Identified Species: 7.88
UniProt: Q96KR1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96KR1 NP_057191.2 1074 117012 S546 E V K Q D T V S E P V T P A S
Chimpanzee Pan troglodytes XP_001155370 1030 112531 E527 V G H D Y V E E V R N D E G K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_546357 1073 116879 E546 V K P D T V S E P V T P A S L
Cat Felis silvestris
Mouse Mus musculus O88532 1074 116840 S546 E V K Q D A G S E P V T P A S
Rat Rattus norvegicus Q562A2 1073 116800 V544 P E V K Q D A V S E P V T P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508407 1102 120156 P574 E V K Q D T T P E P V T P S T
Chicken Gallus gallus XP_424997 1045 113993 A526 P V T P T T L A A L Q S D V Q
Frog Xenopus laevis Q6GPM1 1054 115199 L537 A A Q T L A A L Q S D V Q P V
Zebra Danio Brachydanio rerio Q6PCR6 1074 116505 D540 D A K N D M P D P M S P Q S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_788510 884 96010 N472 Q R F G R M G N G P P P H F G
Honey Bee Apis mellifera XP_624428 928 100974 M516 P M M D E E M M Y W E E R R R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001182008 936 104584 R524 R Y W E E R R R F E Q E M E Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.8 N.A. 98.9 N.A. 97.7 94.4 N.A. 89.2 90.5 84.8 80.2 N.A. 39.1 47.2 N.A. 43.2
Protein Similarity: 100 95.9 N.A. 99.6 N.A. 99 96.4 N.A. 93 94 91.9 88.6 N.A. 52.3 58.8 N.A. 56.4
P-Site Identity: 100 0 N.A. 0 N.A. 86.6 0 N.A. 73.3 13.3 0 13.3 N.A. 6.6 0 N.A. 0
P-Site Similarity: 100 0 N.A. 6.6 N.A. 86.6 13.3 N.A. 86.6 33.3 13.3 33.3 N.A. 20 20 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 17 0 0 0 17 17 9 9 0 0 0 9 17 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 25 34 9 0 9 0 0 9 9 9 0 0 % D
% Glu: 25 9 0 9 17 9 9 17 25 17 9 17 9 9 0 % E
% Phe: 0 0 9 0 0 0 0 0 9 0 0 0 0 9 0 % F
% Gly: 0 9 0 9 0 0 17 0 9 0 0 0 0 9 9 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 9 34 9 0 0 0 0 0 0 0 0 0 0 9 % K
% Leu: 0 0 0 0 9 0 9 9 0 9 0 0 0 0 9 % L
% Met: 0 9 9 0 0 17 9 9 0 9 0 0 9 0 0 % M
% Asn: 0 0 0 9 0 0 0 9 0 0 9 0 0 0 0 % N
% Pro: 25 0 9 9 0 0 9 9 17 34 17 25 25 17 0 % P
% Gln: 9 0 9 25 9 0 0 0 9 0 17 0 17 0 9 % Q
% Arg: 9 9 0 0 9 9 9 9 0 9 0 0 9 9 9 % R
% Ser: 0 0 0 0 0 0 9 17 9 9 9 9 0 25 17 % S
% Thr: 0 0 9 9 17 25 9 0 0 0 9 25 9 0 9 % T
% Val: 17 34 9 0 0 17 9 9 9 9 25 17 0 9 9 % V
% Trp: 0 0 9 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 0 9 0 0 9 0 0 0 9 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _