Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CALR3 All Species: 16.36
Human Site: S190 Identified Species: 24
UniProt: Q96L12 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96L12 NP_659483.2 384 44996 S190 D V K I D G Q S I E S G S I E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001110217 417 48095 Q190 E V K I D N S Q V E S G S L E
Dog Lupus familis XP_533885 385 44743 S190 E V K I D G Q S I E S G G I E
Cat Felis silvestris
Mouse Mus musculus Q9D9Q6 380 44179 S190 E V K V D G Q S I E S G S I E
Rat Rattus norvegicus P18418 416 47977 Q190 E V K I D N S Q V E S G S L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511427 410 46822 S194 K V R I D A K S V A S G N I N
Chicken Gallus gallus XP_418262 419 48016 V203 E V K I D N E V A A L G N L E
Frog Xenopus laevis NP_001080765 413 48503 K191 E V K I D N S K V E S G S L E
Zebra Danio Brachydanio rerio NP_571122 417 48705 K190 E V K I D N E K V E S G S L E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P29413 406 46790 K190 E V L I D N E K V E S G N L E
Honey Bee Apis mellifera XP_392689 403 47156 E189 K V L I D N E E V E S G E L E
Nematode Worm Caenorhab. elegans P27798 395 45598 S185 E V K I D G E S A Q T G S L E
Sea Urchin Strong. purpuratus NP_999643 421 48804 K189 E V R I D N E K A Q A G N L E
Poplar Tree Populus trichocarpa
Maize Zea mays Q9SP22 420 47921 E196 S I L I D N E E K H T G S I Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38858 424 48138 E193 S I L I D N V E K Q T G S L Y
Baker's Yeast Sacchar. cerevisiae P27825 502 56949 D232 M V R E H I E D K K K V N F E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 47.4 86.4 N.A. 82.5 47.8 N.A. 50.7 51 48.4 47 N.A. 40.3 44.9 45.8 43.9
Protein Similarity: 100 N.A. 64.7 93.5 N.A. 90.6 65.6 N.A. 67.3 66.8 65.6 65.2 N.A. 59.3 62 64 62.7
P-Site Identity: 100 N.A. 60 86.6 N.A. 86.6 60 N.A. 46.6 40 60 60 N.A. 46.6 46.6 60 33.3
P-Site Similarity: 100 N.A. 80 93.3 N.A. 100 80 N.A. 73.3 66.6 80 86.6 N.A. 80 66.6 93.3 80
Percent
Protein Identity: N.A. 37.8 N.A. 39.8 21.3 N.A.
Protein Similarity: N.A. 55.7 N.A. 56.3 39.6 N.A.
P-Site Identity: N.A. 33.3 N.A. 26.6 13.3 N.A.
P-Site Similarity: N.A. 53.3 N.A. 53.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 7 0 0 19 13 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 94 0 0 7 0 0 0 0 0 0 0 % D
% Glu: 63 0 0 7 0 0 50 19 0 57 0 0 7 0 82 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % F
% Gly: 0 0 0 0 0 25 0 0 0 0 0 94 7 0 0 % G
% His: 0 0 0 0 7 0 0 0 0 7 0 0 0 0 0 % H
% Ile: 0 13 0 88 0 7 0 0 19 0 0 0 0 32 0 % I
% Lys: 13 0 57 0 0 0 7 25 19 7 7 0 0 0 0 % K
% Leu: 0 0 25 0 0 0 0 0 0 0 7 0 0 63 0 % L
% Met: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 63 0 0 0 0 0 0 32 0 7 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 19 13 0 19 0 0 0 0 0 % Q
% Arg: 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 13 0 0 0 0 0 19 32 0 0 63 0 57 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 % T
% Val: 0 88 0 7 0 0 7 7 44 0 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _