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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CALR3 All Species: 9.09
Human Site: S204 Identified Species: 13.33
UniProt: Q96L12 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96L12 NP_659483.2 384 44996 S204 E Y D W N L T S L K K E T S P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001110217 417 48095 P204 E D D W D F L P P K K I K D P
Dog Lupus familis XP_533885 385 44743 S204 E Y D W N L T S L K K M E K T
Cat Felis silvestris
Mouse Mus musculus Q9D9Q6 380 44179 S204 E Y D W N L T S L R K T E K T
Rat Rattus norvegicus P18418 416 47977 P204 E D D W D F L P P K K I K D P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511427 410 46822 S208 N D D W D F L S L G K I K N P
Chicken Gallus gallus XP_418262 419 48016 P217 E D D L D F L P P R K I N D P
Frog Xenopus laevis NP_001080765 413 48503 P205 E E D W D F L P P K K I K D P
Zebra Danio Brachydanio rerio NP_571122 417 48705 P204 E E D W D F L P P K K I K D P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P29413 406 46790 A204 E D D W D F L A P K K I K D P
Honey Bee Apis mellifera XP_392689 403 47156 P203 E A D W D F L P P K K I K D P
Nematode Worm Caenorhab. elegans P27798 395 45598 P199 E E D W D L L P A K K I K D P
Sea Urchin Strong. purpuratus NP_999643 421 48804 P203 E E D W D F L P S K M I R D P
Poplar Tree Populus trichocarpa
Maize Zea mays Q9SP22 420 47921 P210 Y E H W D I L P P K K I K D P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38858 424 48138 P207 Y S D W D L L P P K K I K D P
Baker's Yeast Sacchar. cerevisiae P27825 502 56949 L246 E P P I T P P L M I P D V S V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 47.4 86.4 N.A. 82.5 47.8 N.A. 50.7 51 48.4 47 N.A. 40.3 44.9 45.8 43.9
Protein Similarity: 100 N.A. 64.7 93.5 N.A. 90.6 65.6 N.A. 67.3 66.8 65.6 65.2 N.A. 59.3 62 64 62.7
P-Site Identity: 100 N.A. 40 73.3 N.A. 66.6 40 N.A. 40 26.6 40 40 N.A. 40 40 46.6 33.3
P-Site Similarity: 100 N.A. 46.6 73.3 N.A. 73.3 46.6 N.A. 53.3 40 46.6 46.6 N.A. 53.3 46.6 53.3 40
Percent
Protein Identity: N.A. 37.8 N.A. 39.8 21.3 N.A.
Protein Similarity: N.A. 55.7 N.A. 56.3 39.6 N.A.
P-Site Identity: N.A. 26.6 N.A. 40 13.3 N.A.
P-Site Similarity: N.A. 40 N.A. 46.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 0 7 7 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 32 88 0 75 0 0 0 0 0 0 7 0 69 0 % D
% Glu: 82 32 0 0 0 0 0 0 0 0 0 7 13 0 0 % E
% Phe: 0 0 0 0 0 57 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 7 0 0 0 7 0 75 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 75 88 0 63 13 0 % K
% Leu: 0 0 0 7 0 32 75 7 25 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 7 0 7 7 0 0 0 % M
% Asn: 7 0 0 0 19 0 0 0 0 0 0 0 7 7 0 % N
% Pro: 0 7 7 0 0 7 7 63 57 0 7 0 0 0 82 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 13 0 0 7 0 0 % R
% Ser: 0 7 0 0 0 0 0 25 7 0 0 0 0 13 0 % S
% Thr: 0 0 0 0 7 0 19 0 0 0 0 7 7 0 13 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 7 % V
% Trp: 0 0 0 88 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 13 19 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _