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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CALR3
All Species:
2.12
Human Site:
S210
Identified Species:
3.11
UniProt:
Q96L12
Number Species:
15
Phosphosite Substitution
Charge Score:
0.6
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96L12
NP_659483.2
384
44996
S210
T
S
L
K
K
E
T
S
P
A
E
S
K
D
W
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110217
417
48095
D210
L
P
P
K
K
I
K
D
P
D
A
S
K
P
E
Dog
Lupus familis
XP_533885
385
44743
K210
T
S
L
K
K
M
E
K
T
S
A
E
S
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9D9Q6
380
44179
K210
T
S
L
R
K
T
E
K
T
S
L
D
S
R
D
Rat
Rattus norvegicus
P18418
416
47977
D210
L
P
P
K
K
I
K
D
P
D
A
A
K
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511427
410
46822
N214
L
S
L
G
K
I
K
N
P
S
S
K
R
P
E
Chicken
Gallus gallus
XP_418262
419
48016
D223
L
P
P
R
K
I
N
D
P
A
V
K
K
P
S
Frog
Xenopus laevis
NP_001080765
413
48503
D211
L
P
P
K
K
I
K
D
P
E
A
K
K
P
D
Zebra Danio
Brachydanio rerio
NP_571122
417
48705
D210
L
P
P
K
K
I
K
D
P
E
A
K
K
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29413
406
46790
D210
L
A
P
K
K
I
K
D
P
T
A
T
K
P
E
Honey Bee
Apis mellifera
XP_392689
403
47156
D209
L
P
P
K
K
I
K
D
P
S
Q
S
K
P
E
Nematode Worm
Caenorhab. elegans
P27798
395
45598
D205
L
P
A
K
K
I
K
D
P
D
A
K
K
P
E
Sea Urchin
Strong. purpuratus
NP_999643
421
48804
D209
L
P
S
K
M
I
R
D
P
E
A
K
K
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SP22
420
47921
D216
L
P
P
K
K
I
K
D
P
E
A
K
K
P
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38858
424
48138
D213
L
P
P
K
K
I
K
D
P
S
A
K
K
P
E
Baker's Yeast
Sacchar. cerevisiae
P27825
502
56949
S252
P
L
M
I
P
D
V
S
V
A
K
P
H
D
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
47.4
86.4
N.A.
82.5
47.8
N.A.
50.7
51
48.4
47
N.A.
40.3
44.9
45.8
43.9
Protein Similarity:
100
N.A.
64.7
93.5
N.A.
90.6
65.6
N.A.
67.3
66.8
65.6
65.2
N.A.
59.3
62
64
62.7
P-Site Identity:
100
N.A.
33.3
33.3
N.A.
26.6
26.6
N.A.
26.6
26.6
26.6
26.6
N.A.
26.6
33.3
26.6
20
P-Site Similarity:
100
N.A.
33.3
40
N.A.
40
33.3
N.A.
46.6
33.3
26.6
26.6
N.A.
40
46.6
26.6
20
Percent
Protein Identity:
N.A.
37.8
N.A.
39.8
21.3
N.A.
Protein Similarity:
N.A.
55.7
N.A.
56.3
39.6
N.A.
P-Site Identity:
N.A.
26.6
N.A.
26.6
26.6
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
33.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
0
0
0
0
19
63
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
69
0
19
0
7
0
13
25
% D
% Glu:
0
0
0
0
0
7
13
0
0
25
7
7
0
0
57
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
7
0
75
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
75
88
0
63
13
0
0
7
50
75
7
0
% K
% Leu:
75
7
25
0
0
0
0
0
0
0
7
0
0
0
0
% L
% Met:
0
0
7
0
7
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% N
% Pro:
7
63
57
0
7
0
0
0
82
0
0
7
0
75
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% Q
% Arg:
0
0
0
13
0
0
7
0
0
0
0
0
7
7
0
% R
% Ser:
0
25
7
0
0
0
0
13
0
32
7
19
13
0
7
% S
% Thr:
19
0
0
0
0
7
7
0
13
7
0
7
0
0
0
% T
% Val:
0
0
0
0
0
0
7
0
7
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _