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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CALR3 All Species: 23.33
Human Site: S44 Identified Species: 34.22
UniProt: Q96L12 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96L12 NP_659483.2 384 44996 S44 W L Q S T N D S R F G H F R L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001110217 417 48095 S44 W I E S K H K S D F G K F V L
Dog Lupus familis XP_533885 385 44743 S44 W V Q S T N D S Q I G H F R L
Cat Felis silvestris
Mouse Mus musculus Q9D9Q6 380 44179 S44 W V Q S T N D S Q F G H F R V
Rat Rattus norvegicus P18418 416 47977 S44 W V E S K H K S D F G K F V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511427 410 46822 P48 W L Q S T H D P N F G K F K L
Chicken Gallus gallus XP_418262 419 48016 P57 W V S S E S R P D L G T F Q L
Frog Xenopus laevis NP_001080765 413 48503 S45 W V E S K H K S D Y G K F K L
Zebra Danio Brachydanio rerio NP_571122 417 48705 S44 W V E S K H K S D Y G Q W K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P29413 406 46790 K44 I Y S K H P G K E F G K F V L
Honey Bee Apis mellifera XP_392689 403 47156 K43 V Y S E H P G K E F G K F I L
Nematode Worm Caenorhab. elegans P27798 395 45598 D39 W V Q S K H K D D F G A F K L
Sea Urchin Strong. purpuratus NP_999643 421 48804 S43 V E S V H K G S D A G K F K W
Poplar Tree Populus trichocarpa
Maize Zea mays Q9SP22 420 47921 E50 K S E W K K D E N M A G E W N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38858 424 48138 D47 K S E W K K D D N T A G E W K
Baker's Yeast Sacchar. cerevisiae P27825 502 56949 Y64 N N E G S K I Y G A Q W R L S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 47.4 86.4 N.A. 82.5 47.8 N.A. 50.7 51 48.4 47 N.A. 40.3 44.9 45.8 43.9
Protein Similarity: 100 N.A. 64.7 93.5 N.A. 90.6 65.6 N.A. 67.3 66.8 65.6 65.2 N.A. 59.3 62 64 62.7
P-Site Identity: 100 N.A. 46.6 80 N.A. 80 46.6 N.A. 66.6 33.3 40 33.3 N.A. 26.6 26.6 46.6 20
P-Site Similarity: 100 N.A. 66.6 93.3 N.A. 100 66.6 N.A. 80 53.3 73.3 73.3 N.A. 26.6 26.6 66.6 26.6
Percent
Protein Identity: N.A. 37.8 N.A. 39.8 21.3 N.A.
Protein Similarity: N.A. 55.7 N.A. 56.3 39.6 N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 0 N.A.
P-Site Similarity: N.A. 13.3 N.A. 13.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 13 13 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 38 13 44 0 0 0 0 0 0 % D
% Glu: 0 7 44 7 7 0 0 7 13 0 0 0 13 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 50 0 0 75 0 0 % F
% Gly: 0 0 0 7 0 0 19 0 7 0 82 13 0 0 0 % G
% His: 0 0 0 0 19 38 0 0 0 0 0 19 0 0 0 % H
% Ile: 7 7 0 0 0 0 7 0 0 7 0 0 0 7 0 % I
% Lys: 13 0 0 7 44 25 32 13 0 0 0 44 0 32 7 % K
% Leu: 0 13 0 0 0 0 0 0 0 7 0 0 0 7 69 % L
% Met: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % M
% Asn: 7 7 0 0 0 19 0 0 19 0 0 0 0 0 7 % N
% Pro: 0 0 0 0 0 13 0 13 0 0 0 0 0 0 0 % P
% Gln: 0 0 32 0 0 0 0 0 13 0 7 7 0 7 0 % Q
% Arg: 0 0 0 0 0 0 7 0 7 0 0 0 7 19 0 % R
% Ser: 0 13 25 63 7 7 0 50 0 0 0 0 0 0 7 % S
% Thr: 0 0 0 0 25 0 0 0 0 7 0 7 0 0 0 % T
% Val: 13 44 0 7 0 0 0 0 0 0 0 0 0 19 7 % V
% Trp: 63 0 0 13 0 0 0 0 0 0 0 7 7 13 7 % W
% Tyr: 0 13 0 0 0 0 0 7 0 13 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _