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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CALR3 All Species: 12.73
Human Site: T41 Identified Species: 18.67
UniProt: Q96L12 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.4
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96L12 NP_659483.2 384 44996 T41 R N R W L Q S T N D S R F G H
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001110217 417 48095 K41 T S R W I E S K H K S D F G K
Dog Lupus familis XP_533885 385 44743 T41 R N R W V Q S T N D S Q I G H
Cat Felis silvestris
Mouse Mus musculus Q9D9Q6 380 44179 T41 R N R W V Q S T N D S Q F G H
Rat Rattus norvegicus P18418 416 47977 K41 T N R W V E S K H K S D F G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511427 410 46822 T45 K K R W L Q S T H D P N F G K
Chicken Gallus gallus XP_418262 419 48016 E54 R K R W V S S E S R P D L G T
Frog Xenopus laevis NP_001080765 413 48503 K42 T Q R W V E S K H K S D Y G K
Zebra Danio Brachydanio rerio NP_571122 417 48705 K41 K S R W V E S K H K S D Y G Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P29413 406 46790 H41 D T W I Y S K H P G K E F G K
Honey Bee Apis mellifera XP_392689 403 47156 H40 K N W V Y S E H P G K E F G K
Nematode Worm Caenorhab. elegans P27798 395 45598 K36 E K R W V Q S K H K D D F G A
Sea Urchin Strong. purpuratus NP_999643 421 48804 H40 S R W V E S V H K G S D A G K
Poplar Tree Populus trichocarpa
Maize Zea mays Q9SP22 420 47921 K47 R W V K S E W K K D E N M A G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38858 424 48138 K44 R W V K S E W K K D D N T A G
Baker's Yeast Sacchar. cerevisiae P27825 502 56949 S61 E A V N N E G S K I Y G A Q W
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 47.4 86.4 N.A. 82.5 47.8 N.A. 50.7 51 48.4 47 N.A. 40.3 44.9 45.8 43.9
Protein Similarity: 100 N.A. 64.7 93.5 N.A. 90.6 65.6 N.A. 67.3 66.8 65.6 65.2 N.A. 59.3 62 64 62.7
P-Site Identity: 100 N.A. 40 80 N.A. 86.6 46.6 N.A. 60 33.3 33.3 33.3 N.A. 13.3 20 40 13.3
P-Site Similarity: 100 N.A. 66.6 93.3 N.A. 100 66.6 N.A. 73.3 46.6 60 73.3 N.A. 13.3 26.6 53.3 13.3
Percent
Protein Identity: N.A. 37.8 N.A. 39.8 21.3 N.A.
Protein Similarity: N.A. 55.7 N.A. 56.3 39.6 N.A.
P-Site Identity: N.A. 13.3 N.A. 13.3 0 N.A.
P-Site Similarity: N.A. 20 N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 0 0 0 0 0 0 13 13 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 0 0 0 38 13 44 0 0 0 % D
% Glu: 13 0 0 0 7 44 7 7 0 0 7 13 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 50 0 0 % F
% Gly: 0 0 0 0 0 0 7 0 0 19 0 7 0 82 13 % G
% His: 0 0 0 0 0 0 0 19 38 0 0 0 0 0 19 % H
% Ile: 0 0 0 7 7 0 0 0 0 7 0 0 7 0 0 % I
% Lys: 19 19 0 13 0 0 7 44 25 32 13 0 0 0 44 % K
% Leu: 0 0 0 0 13 0 0 0 0 0 0 0 7 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 32 0 7 7 0 0 0 19 0 0 19 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 13 0 13 0 0 0 0 % P
% Gln: 0 7 0 0 0 32 0 0 0 0 0 13 0 7 7 % Q
% Arg: 38 7 63 0 0 0 0 0 0 7 0 7 0 0 0 % R
% Ser: 7 13 0 0 13 25 63 7 7 0 50 0 0 0 0 % S
% Thr: 19 7 0 0 0 0 0 25 0 0 0 0 7 0 7 % T
% Val: 0 0 19 13 44 0 7 0 0 0 0 0 0 0 0 % V
% Trp: 0 13 19 63 0 0 13 0 0 0 0 0 0 0 7 % W
% Tyr: 0 0 0 0 13 0 0 0 0 0 7 0 13 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _