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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CALR3 All Species: 52.42
Human Site: Y128 Identified Species: 76.89
UniProt: Q96L12 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96L12 NP_659483.2 384 44996 Y128 N L N G K S Q Y Y I M F G P D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001110217 417 48095 Y128 D M H G D S E Y N I M F G P D
Dog Lupus familis XP_533885 385 44743 Y128 N L N G K S Q Y Y I M F G P D
Cat Felis silvestris
Mouse Mus musculus Q9D9Q6 380 44179 Y128 K M N G K S Q Y Y I M F G P D
Rat Rattus norvegicus P18418 416 47977 Y128 D M H G D S E Y N I M F G P D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511427 410 46822 Y132 N L S E N S Y Y Y I M F G P D
Chicken Gallus gallus XP_418262 419 48016 Y141 N L S G A S P Y Y I M F G P D
Frog Xenopus laevis NP_001080765 413 48503 Y129 E M H G E S E Y N I M F G P D
Zebra Danio Brachydanio rerio NP_571122 417 48705 Y128 E M H G E S Q Y Y I M F G P D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P29413 406 46790 Y128 D M H G E S P Y E I M F G P D
Honey Bee Apis mellifera XP_392689 403 47156 Y127 D M H G D S P Y Q I M F G P D
Nematode Worm Caenorhab. elegans P27798 395 45598 Y124 D F H G E T P Y N V M F G P D
Sea Urchin Strong. purpuratus NP_999643 421 48804 Y127 D M H G D S P Y N I M F G P D
Poplar Tree Populus trichocarpa
Maize Zea mays Q9SP22 420 47921 Y134 T L G G D T S Y S I I S R P D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38858 424 48138 Y131 K F G G D T P Y S I M F G P D
Baker's Yeast Sacchar. cerevisiae P27825 502 56949 V152 Y A P D T E G V E L V F G P D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 47.4 86.4 N.A. 82.5 47.8 N.A. 50.7 51 48.4 47 N.A. 40.3 44.9 45.8 43.9
Protein Similarity: 100 N.A. 64.7 93.5 N.A. 90.6 65.6 N.A. 67.3 66.8 65.6 65.2 N.A. 59.3 62 64 62.7
P-Site Identity: 100 N.A. 60 100 N.A. 86.6 60 N.A. 73.3 80 60 73.3 N.A. 60 60 46.6 60
P-Site Similarity: 100 N.A. 86.6 100 N.A. 93.3 86.6 N.A. 80 86.6 86.6 93.3 N.A. 86.6 80 80 80
Percent
Protein Identity: N.A. 37.8 N.A. 39.8 21.3 N.A.
Protein Similarity: N.A. 55.7 N.A. 56.3 39.6 N.A.
P-Site Identity: N.A. 40 N.A. 53.3 26.6 N.A.
P-Site Similarity: N.A. 53.3 N.A. 60 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 7 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 38 0 0 7 38 0 0 0 0 0 0 0 0 0 100 % D
% Glu: 13 0 0 7 25 7 19 0 13 0 0 0 0 0 0 % E
% Phe: 0 13 0 0 0 0 0 0 0 0 0 94 0 0 0 % F
% Gly: 0 0 13 88 0 0 7 0 0 0 0 0 94 0 0 % G
% His: 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 88 7 0 0 0 0 % I
% Lys: 13 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 32 0 0 0 0 0 0 0 7 0 0 0 0 0 % L
% Met: 0 50 0 0 0 0 0 0 0 0 88 0 0 0 0 % M
% Asn: 25 0 19 0 7 0 0 0 32 0 0 0 0 0 0 % N
% Pro: 0 0 7 0 0 0 38 0 0 0 0 0 0 100 0 % P
% Gln: 0 0 0 0 0 0 25 0 7 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % R
% Ser: 0 0 13 0 0 75 7 0 13 0 0 7 0 0 0 % S
% Thr: 7 0 0 0 7 19 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 7 0 7 7 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 7 94 38 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _