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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CALR3
All Species:
28.79
Human Site:
Y324
Identified Species:
42.22
UniProt:
Q96L12
Number Species:
15
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96L12
NP_659483.2
384
44996
Y324
L
I
T
D
D
E
E
Y
A
D
N
F
G
K
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110217
417
48095
Y338
L
I
T
N
D
E
A
Y
A
E
E
F
G
N
E
Dog
Lupus familis
XP_533885
385
44743
Y325
L
I
T
D
D
E
E
Y
A
E
N
F
G
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D9Q6
380
44179
Y321
L
I
T
D
D
E
E
Y
A
E
K
F
G
K
A
Rat
Rattus norvegicus
P18418
416
47977
Y338
L
I
T
N
D
E
A
Y
A
E
E
F
G
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511427
410
46822
Y357
L
I
T
D
S
E
E
Y
A
K
D
F
G
E
Q
Chicken
Gallus gallus
XP_418262
419
48016
Y351
L
I
T
D
D
E
D
Y
A
E
D
F
G
D
E
Frog
Xenopus laevis
NP_001080765
413
48503
Y339
L
M
T
N
D
E
K
Y
A
E
E
Y
G
N
E
Zebra Danio
Brachydanio rerio
NP_571122
417
48705
E338
L
I
T
D
D
V
E
E
A
E
K
F
G
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29413
406
46790
L338
L
I
T
D
D
V
E
L
A
A
K
A
A
A
E
Honey Bee
Apis mellifera
XP_392689
403
47156
V337
L
I
T
D
D
P
E
V
A
R
K
F
G
E
E
Nematode Worm
Caenorhab. elegans
P27798
395
45598
E333
I
I
T
D
S
V
E
E
A
E
A
H
A
A
E
Sea Urchin
Strong. purpuratus
NP_999643
421
48804
E337
L
I
T
D
D
L
E
E
A
E
K
Q
A
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SP22
420
47921
L345
I
I
T
D
D
P
A
L
A
K
T
F
A
E
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38858
424
48138
Y342
L
I
C
D
D
P
D
Y
A
K
K
L
A
D
E
Baker's Yeast
Sacchar. cerevisiae
P27825
502
56949
I408
S
G
S
P
N
M
L
I
S
N
I
Y
V
G
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
47.4
86.4
N.A.
82.5
47.8
N.A.
50.7
51
48.4
47
N.A.
40.3
44.9
45.8
43.9
Protein Similarity:
100
N.A.
64.7
93.5
N.A.
90.6
65.6
N.A.
67.3
66.8
65.6
65.2
N.A.
59.3
62
64
62.7
P-Site Identity:
100
N.A.
60
93.3
N.A.
86.6
60
N.A.
66.6
66.6
46.6
60
N.A.
46.6
60
33.3
53.3
P-Site Similarity:
100
N.A.
73.3
100
N.A.
93.3
73.3
N.A.
80
86.6
80
66.6
N.A.
46.6
66.6
46.6
60
Percent
Protein Identity:
N.A.
37.8
N.A.
39.8
21.3
N.A.
Protein Similarity:
N.A.
55.7
N.A.
56.3
39.6
N.A.
P-Site Identity:
N.A.
40
N.A.
40
0
N.A.
P-Site Similarity:
N.A.
53.3
N.A.
46.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
19
0
94
7
7
7
32
13
19
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
75
82
0
13
0
0
7
13
0
0
13
13
% D
% Glu:
0
0
0
0
0
50
57
19
0
57
19
0
0
19
57
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
63
0
0
0
% F
% Gly:
0
7
0
0
0
0
0
0
0
0
0
0
63
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
13
88
0
0
0
0
0
7
0
0
7
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
7
0
0
19
38
0
0
25
7
% K
% Leu:
82
0
0
0
0
7
7
13
0
0
0
7
0
0
0
% L
% Met:
0
7
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
19
7
0
0
0
0
7
13
0
0
19
0
% N
% Pro:
0
0
0
7
0
19
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% R
% Ser:
7
0
7
0
13
0
0
0
7
0
0
0
0
0
0
% S
% Thr:
0
0
88
0
0
0
0
0
0
0
7
0
0
7
0
% T
% Val:
0
0
0
0
0
19
0
7
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
57
0
0
0
13
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _