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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MARK4 All Species: 6.67
Human Site: S45 Identified Species: 13.33
UniProt: Q96L34 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96L34 NP_113605.2 752 82520 S45 L G A R C R N S I A S C P E E
Chimpanzee Pan troglodytes XP_512745 736 81102 R45 Q P H V G N Y R L L R T I G K
Rhesus Macaque Macaca mulatta XP_001105523 666 73735 A44 E K D E G C L A V C D L R L K
Dog Lupus familis XP_541564 690 76525 Y46 E Q P H V G N Y R L L R T I G
Cat Felis silvestris
Mouse Mus musculus Q8CIP4 752 82625 S45 L G A R C R N S I A S C P E E
Rat Rattus norvegicus Q8VHF0 797 88733 S45 R C R N S I A S C A D E Q P H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508081 736 82480 G46 A D E Q P H I G N Y R L L K T
Chicken Gallus gallus Q9IA88 798 88848 R46 V V K L A R H R V T K T Q V A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 A45 H P V A H R S A A A A C R P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9TW45 1192 126331 S156 Q S G M S S R S A A R R N D Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92958 512 58671
Baker's Yeast Sacchar. cerevisiae P06782 633 72027 P11 N N N T N T A P A N A N S S H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.8 75.8 88.4 N.A. 97.6 60.4 N.A. 64.4 32.4 N.A. 29.3 N.A. N.A. N.A. 34.8 N.A.
Protein Similarity: 100 94.4 77.9 89.3 N.A. 98.9 73.5 N.A. 77.3 50 N.A. 41.2 N.A. N.A. N.A. 46.9 N.A.
P-Site Identity: 100 0 0 6.6 N.A. 100 13.3 N.A. 0 6.6 N.A. 20 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 100 13.3 20 6.6 N.A. 100 13.3 N.A. 13.3 26.6 N.A. 40 N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 27.5 27.7 N.A.
Protein Similarity: N.A. N.A. N.A. 43.8 44.6 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 17 9 9 0 17 17 25 42 17 0 0 0 9 % A
% Cys: 0 9 0 0 17 9 0 0 9 9 0 25 0 0 0 % C
% Asp: 0 9 9 0 0 0 0 0 0 0 17 0 0 9 0 % D
% Glu: 17 0 9 9 0 0 0 0 0 0 0 9 0 17 17 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 17 9 0 17 9 0 9 0 0 0 0 0 9 9 % G
% His: 9 0 9 9 9 9 9 0 0 0 0 0 0 0 17 % H
% Ile: 0 0 0 0 0 9 9 0 17 0 0 0 9 9 0 % I
% Lys: 0 9 9 0 0 0 0 0 0 0 9 0 0 9 17 % K
% Leu: 17 0 0 9 0 0 9 0 9 17 9 17 9 9 0 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 9 9 9 9 9 25 0 9 9 0 9 9 0 0 % N
% Pro: 0 17 9 0 9 0 0 9 0 0 0 0 17 17 9 % P
% Gln: 17 9 0 9 0 0 0 0 0 0 0 0 17 0 9 % Q
% Arg: 9 0 9 17 0 34 9 17 9 0 25 17 17 0 0 % R
% Ser: 0 9 0 0 17 9 9 34 0 0 17 0 9 9 0 % S
% Thr: 0 0 0 9 0 9 0 0 0 9 0 17 9 0 9 % T
% Val: 9 9 9 9 9 0 0 0 17 0 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 9 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _